HitPredict

Interactor 1: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12538641
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030276 - clathrin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 949 Hs			1 576
+	Hs
		1014011 AP1B1_HUMAN (1-949): 0: 978: 100.00		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Rn
		291389 AP2B1_RAT (1-949): 0: 944: 81.45		EPN1_RAT (1-576): 2.54e-91: 293: 94.27
+	Hs
		925867 AP2B1_HUMAN (1-949): 0: 944: 81.45		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		926065 AP2B1_HUMAN (1-949): 0: 944: 81.45		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Rn
		923862 AP2B1_RAT (1-949): 0: 944: 81.45		EPN2_RAT (1-562): 1.86e-67: 231: 42.44
+	Hs
		307524 AP2B1_HUMAN (1-949): 0: 944: 81.45		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Dm
		1096902 Q24253_DROME (1-949): 0: 851: 72.74		Q8IN05_DROME (3-440): 8.77e-82: 281: 26.81
+	Hs
		203223 AP1B1_HUMAN (1-949): 0: 978: 100.00		SYNJ1_HUMAN (246-573): 8.14e-20: 96.3: 14.11
+	Dm
		1096905 Q24253_DROME (1-949): 0: 851: 72.74		Q9VD13_DROME (3-568): 9.72e-62: 217: 23.13
+	Hs
		203219 AP2B1_HUMAN (1-949): 0: 944: 81.45		SYNJ1_HUMAN (246-573): 8.14e-20: 96.3: 14.11
+	Hs
		321545 AP2A1_HUMAN (12-943): 0: 677: 18.58		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		321680 AP2A1_HUMAN (12-943): 0: 677: 18.58		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Rn
		88757 D3ZUY8_RAT (12-943): 0: 670: 18.03		EPN1_RAT (1-576): 2.54e-91: 293: 94.27
+	Rn
		291387 AP2A2_RAT (12-945): 0: 635: 17.94		EPN1_RAT (1-576): 2.54e-91: 293: 94.27
+	Rn
		291395 Q66HM2_RAT (12-945): 0: 631: 17.92		EPN1_RAT (1-576): 2.54e-91: 293: 94.27
+	Hs
		302148 AP2A2_HUMAN (12-945): 0: 625: 18.33		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	At
		1228257 AP2A1_ARATH (13-946): 0: 627: 16.87		EPN1_ARATH (2-453): 4.14e-71: 240: 21.26
+	At
		1147101 AP2A1_ARATH (13-946): 0: 627: 16.87		EPN2_ARATH (2-574): 1.39e-39: 156: 21.89
+	Hs
		203194 AP2A1_HUMAN (12-943): 0: 677: 18.58		SYNJ1_HUMAN (246-573): 8.14e-20: 96.3: 14.11
+	Rn
		1144064 Q66HM2_RAT (12-945): 0: 631: 17.92		SYNJ1_RAT (246-575): 3.51e-15: 81.2: 14.67