HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: Q86V38 (Q86V38)
Atrophin 1
Gene: ATN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1191
+	Hs
		869446 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Hs
		869506 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		ATN1_HUMAN (1-1191): 5.11e-149: 480: 99.83
+	Mm
		903669 WDR5_MOUSE (1-334): 2.77e-131: 379: 100.00		KMT2C_MOUSE (9-928): 3.29e-16: 86.8: 12.57
+	Hs
		903374 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2C_HUMAN (4-711): 6.35e-12: 72.6: 10.59
+	Hs
		903576 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		RERE_HUMAN (3-865): 1.02e-11: 71.8: 8.77
+	Dm
		1370295 POC1_DROME (11-254): 9.16e-70: 224: 25.82		Q9VLS7_DROME (1-859): 2.59e-14: 80.3: 9.82
+	Hs
		1281391 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PRR36_HUMAN (1-552): 1.03e-09: 65.3: 12.27
+	Dm
		1370339 FBXW7_DROME (40-169): 6.72e-18: 86.7: 39.10		Q9VLS7_DROME (1-859): 2.59e-14: 80.3: 9.82
+	Hs
		131738 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		BCL9_HUMAN (105-767): 6.3e-10: 65.9: 11.16