Interactor 1: GET3 (Q12154)
ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Golgi to ER traffic protein 3) (Guided entry of tail-anchored proteins 3)
Gene: GET3

Interactor 2: MDY2 (Q12285)
Ubiquitin-like protein MDY2 (Golgi to ER traffic protein 5) (Mating-deficient protein 2) (Translation machinery-associated protein 24)
Gene: MDY2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 11283351, 18719252, 20106980, 20554915, 28973888, 35189106, 35587358, 19325107, 20850366
Identification Methods two hybrid pooling approach, two hybrid, pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0045048 - protein insertion into ER membrane
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 354
Sc

1 212
+ Hs

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Last updated: 15 Jul 2024