HitPredict

Interactor 1: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	33961781, 25306918, 26811472, 28514442, 23443559
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 499 Hs			1 543
+	Hs
		826632 CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821182 CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573235 CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1306704 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		TCPH_HUMAN (1-543): 0: 647: 100.00
+	At
		1351754 CD203_ARATH (67-499): 1.24e-87: 277: 40.91		TCPH_ARATH (1-529): 0: 583: 67.67
+	Hs
		821437 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		826807 FBXW7_HUMAN (210-496): 2.2e-71: 242: 17.81		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573406 FBXW7_HUMAN (210-496): 2.2e-71: 242: 17.81		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1306738 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		792942 LIS1_HUMAN (337-498): 1.74e-37: 143: 16.56		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Sc
		760773 AMA1_YEAST (162-470): 1.12e-38: 150: 28.65		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		843174 CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		826938 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821355 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573412 SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821460 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		TCPE_HUMAN (3-527): 0: 557: 29.59
+	At
		660213 CD203_ARATH (67-499): 1.24e-87: 277: 40.91		TCPA_ARATH (14-521): 1.16e-93: 298: 36.67
+	Hs
		843411 NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843429 FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Mm
		945959 FZR1_MOUSE (65-303): 4.45e-23: 103: 13.71		TCPD_MOUSE (24-520): 1.62e-90: 289: 34.38