HitPredict

Interactor 1: PR20C (P86479)
Proline-rich protein 20C
Gene: PRR20C

Interactor 2: SIAH1 (Q8IUQ4)
E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a)
Gene: SIAH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 282
+	Hs
		1017597 PR20E_HUMAN (1-221): 8.64e-119: 338: 100.00		SIAH1_HUMAN (1-282): 7.32e-121: 348: 100.00
+	Hs
		1017649 PR20D_HUMAN (1-221): 8.64e-119: 338: 100.00		SIAH1_HUMAN (1-282): 7.32e-121: 348: 100.00
+	Hs
		1017717 PR20A_HUMAN (1-221): 8.64e-119: 338: 100.00		SIAH1_HUMAN (1-282): 7.32e-121: 348: 100.00
+	Hs
		211558 PR20E_HUMAN (1-221): 8.64e-119: 338: 100.00		SIAH2_HUMAN (28-282): 1.74e-103: 306: 83.20
+	Hs
		211559 PR20A_HUMAN (1-221): 8.64e-119: 338: 100.00		SIAH2_HUMAN (28-282): 1.74e-103: 306: 83.20