HitPredict

Interactor 1: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Interactor 2: STXB6 (Q8NFX7)
Syntaxin-binding protein 6 (Amisyn)
Gene: STXBP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin, Sec3-PIP2_bind~Syntaxin, Synaptobrevin~Syntaxin
Common GO terms	GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0035493 - SNARE complex assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 210
+	Hs
		1083961 STX1A_HUMAN (1-293): 1.9e-70: 221: 43.20		STXB6_HUMAN (1-210): 5.54e-103: 297: 100.00
+	Hs
		1030167 STX3_HUMAN (1-295): 6.64e-57: 186: 38.31		STXB6_HUMAN (1-210): 5.54e-103: 297: 100.00
+	Hs
		178677 STX7_HUMAN (31-291): 4.47e-50: 167: 23.95		STXB6_HUMAN (1-210): 5.54e-103: 297: 100.00
+	Hs
		1205346 STX12_HUMAN (34-279): 2.35e-49: 166: 25.00		STXB6_HUMAN (1-210): 5.54e-103: 297: 100.00