HitPredict

Interactor 1: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Interactor 2: MKRN2 (Q9H000)
E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2)
Gene: MKRN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 416
+	Hs
		1031454 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		516684 PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1031488 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		516728 PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		668423 RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1073854 RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1073888 RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		1077530 ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		1023456 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		516487 PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		1023561 PABP3_HUMAN (115-358): 2.14e-42: 157: 20.51		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Dm
		597087 PABP_DROME (40-122): 7.8e-19: 89.7: 30.12		Q9VP20_DROME (28-386): 1.95e-106: 321: 33.70
+	Hs
		1020289 ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		668372 RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55		MBNL2_HUMAN (7-224): 1.03e-35: 136: 13.10
+	Hs
		1031384 PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		1221460 PABP3_HUMAN (115-358): 2.14e-42: 157: 20.51		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		1073800 RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27		ZC3H8_HUMAN (7-55): 1.25e-13: 73: 42.86
+	Hs
		1077539 ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90		ZC3H4_HUMAN (5-55): 8.4e-15: 78.7: 41.18
+	Hs
		1077514 ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90		MBNL1_HUMAN (1-168): 5.44e-09: 59.6: 13.79