HitPredict

Interactor 1: NPR1 (P93002)
Regulatory protein NPR1 (BTB/POZ domain-containing protein NPR1) (Non-inducible immunity protein 1) (Nim1) (Nonexpresser of PR genes 1) (Salicylic acid insensitive 1) (Sai1)
Gene: NPR1

Interactor 2: CUL3A (Q9ZVH4)
Cullin-3A (AtCUL3a)
Gene: CUL3A

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.694

Property	Details
Experiments	19490895, 22699612
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Cullin, BTB~Cullin
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 593 At			1 732
+	At
		1205401 NPR4_ARATH (37-563): 6.93e-93: 298: 38.62		CUL3A_ARATH (1-732): 0: 932: 100.00
+	At
		1318312 NPR3_ARATH (40-562): 3.64e-86: 281: 38.02		CUL3A_ARATH (1-732): 0: 932: 100.00
+	Hs
		1091393 ANK3_HUMAN (174-573): 4.57e-61: 222: 12.93		CUL3_HUMAN (3-732): 0: 843: 51.64
+	Hs
		1091394 ANK3_HUMAN (174-573): 4.57e-61: 222: 12.93		CUL4A_HUMAN (6-732): 0: 822: 38.75
+	Hs
		177215 ANR28_HUMAN (201-588): 1.76e-54: 201: 14.39		CUL3_HUMAN (3-732): 0: 843: 51.64
+	Hs
		592933 ANK1_HUMAN (191-516): 9.91e-52: 194: 11.78		CUL3_HUMAN (3-732): 0: 843: 51.64
+	Hs
		1114922 MIB1_HUMAN (208-505): 5.68e-43: 167: 19.33		CUL4A_HUMAN (6-732): 0: 822: 38.75
+	Hs
		1115286 MIB1_HUMAN (208-505): 5.68e-43: 167: 19.33		CUL4B_HUMAN (4-732): 0: 820: 39.18
+	Hs
		1113629 ANKH1_HUMAN (317-499): 2.56e-29: 126: 15.05		CUL3_HUMAN (3-732): 0: 843: 51.64
+	Hs
		943938 RIPK4_HUMAN (43-325): 2.82e-30: 128: 13.31		CUL1_HUMAN (25-732): 0: 745: 30.47
+	Hs
		1112713 Q9H4D1_HUMAN (253-456): 9.37e-11: 66.7: 16.89		CUL1_HUMAN (25-732): 0: 745: 30.47
+	Hs
		1371859 TNKS2_HUMAN (171-569): 7.4e-51: 191: 10.43		CUL5_HUMAN (25-732): 0: 579: 23.36