HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0001772 - immunological synapse GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007015 - actin filament organization GO:0007163 - establishment or maintenance of cell polarity and 1 others more... GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 191
+	Hs
		436278 DLG1_HUMAN (1-904): 0: 725: 100.00		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Hs
		915639 DLG1_HUMAN (1-904): 0: 725: 100.00		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		925239 DLG1_HUMAN (1-904): 0: 725: 100.00		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		564500 DLG1_HUMAN (1-904): 0: 725: 100.00		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		893948 DLG1_HUMAN (1-904): 0: 725: 100.00		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		545346 DLG1_HUMAN (1-904): 0: 725: 100.00		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		892341 DLG1_HUMAN (1-904): 0: 725: 100.00		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		950954 DLG1_HUMAN (1-904): 0: 725: 100.00		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		900424 DLG1_HUMAN (1-904): 0: 725: 100.00		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Hs
		915880 DLG3_HUMAN (139-904): 0: 585: 66.28		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		564636 DLG3_HUMAN (139-904): 0: 585: 66.28		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		892525 DLG3_HUMAN (139-904): 0: 585: 66.28		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		951207 DLG3_HUMAN (139-904): 0: 585: 66.28		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		900762 DLG3_HUMAN (139-904): 0: 585: 66.28		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Hs
		159188 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		159189 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		159153 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		159184 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		159149 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		159192 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56