Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
SMAD4
Mothers against decapentaplegic homolog 4 |
4 |
18 |
Small-scale |
0.896 | High |
|
|
SMAD6
Mothers against decapentaplegic homolog 6 |
2 |
19 |
Small-scale |
0.800 | High |
|
|
SMAD2
Mothers against decapentaplegic homolog 2 |
2 |
18 |
Small-scale |
0.768 | High |
|
|
SMUF2
E3 ubiquitin-protein ligase SMURF2 |
19 |
20 |
Small-scale |
0.766 | High |
|
|
TGFR1
TGF-beta receptor type-1 |
19 |
20 |
Small-scale |
0.763 | High |
|
|
SMUF1
E3 ubiquitin-protein ligase SMURF1 |
14 |
20 |
Small-scale |
0.761 | High |
|
|
SMAD3
Mothers against decapentaplegic homolog 3 |
1 |
18 |
Small-scale |
0.713 | High |
|
|
YAP1
Transcriptional coactivator YAP1 |
3 |
20 |
Small-scale |
0.696 | High |
|
|
ITCH
E3 ubiquitin-protein ligase Itchy homolog |
4 |
20 |
Small-scale |
0.691 | High |
|
|
NED4L
E3 ubiquitin-protein ligase NEDD4-like |
3 |
20 |
Small-scale |
0.689 | High |
|
|
RN111
E3 ubiquitin-protein ligase Arkadia |
4 |
9 |
Small-scale |
0.680 | High |
|
|
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
3 |
20 |
Small-scale |
0.675 | High |
|
|
HDAC1
Histone deacetylase 1 |
3 |
12 |
Small-scale |
0.664 | High |
|
|
ACV1B
Activin receptor type-1B |
3 |
20 |
Small-scale |
0.657 | High |
|
|
HDAC3
Histone deacetylase 3 |
3 |
12 |
Small-scale |
0.640 | High |
|
|
TGFR2
TGF-beta receptor type-2 |
3 |
20 |
Small-scale |
0.640 | High |
|
|
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 |
3 |
20 |
Small-scale |
0.640 | High |
|
|
UBP15
Ubiquitin carboxyl-terminal hydrolase 15 |
3 |
12 |
Small-scale |
0.640 | High |
|
|
PIAS4
E3 SUMO-protein ligase PIAS4 |
2 |
16 |
Small-scale |
0.627 | High |
|
|
SMAD9
Mothers against decapentaplegic homolog 9 |
1 |
18 |
Small-scale |
0.618 | High |
|
|
SKI
Ski oncogene |
1 |
16 |
Small-scale |
0.618 | High |
|
|
SMAD1
Mothers against decapentaplegic homolog 1 |
1 |
18 |
Small-scale |
0.618 | High |
|
|
AXIN1
Axin-1 |
2 |
7 |
Small-scale |
0.601 | High |
|
|
CTNB1
Catenin beta-1 |
2 |
5 |
Small-scale |
0.601 | High |
|
|
TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
2 |
4 |
Small-scale |
0.601 | High |
|
|
MK14
Mitogen-activated protein kinase 14 |
2 |
6 |
Small-scale |
0.601 | High |
|
|
LEF1
Lymphoid enhancer-binding factor 1 |
2 |
20 |
Small-scale |
0.601 | High |
|
|
RNF12
E3 ubiquitin-protein ligase RLIM |
2 |
8 |
Small-scale |
0.595 | High |
|
|
AXIN2
Axin-2 |
2 |
7 |
Small-scale |
0.595 | High |
|
|
CSN5
COP9 signalosome complex subunit 5 |
1 |
5 |
Small-scale |
0.594 | High |
|
|
BMR1A
Bone morphogenetic protein receptor type-1A |
2 |
20 |
Small-scale |
0.584 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
2 |
20 |
Small-scale |
0.584 | High |
|
|
UBP11
Ubiquitin carboxyl-terminal hydrolase 11 |
2 |
14 |
Small-scale |
0.584 | High |
|
|
HDAC2
Histone deacetylase 2 |
2 |
12 |
Small-scale |
0.584 | High |
|
|
CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD |
2 |
1 |
Small-scale |
0.584 | High |
|
|
HDAC6
Protein deacetylase HDAC6 |
2 |
17 |
Small-scale |
0.584 | High |
|
|
HDAC5
Histone deacetylase 5 |
2 |
17 |
Small-scale |
0.584 | High |
|
|
STRAP
Serine-threonine kinase receptor-associated protein |
2 |
8 |
Small-scale |
0.584 | High |
|
|
OTUD1
OTU domain-containing protein 1 |
2 |
1 |
Small-scale |
0.579 | High |
|
|
UBP2
Ubiquitin carboxyl-terminal hydrolase 2 |
1 |
13 |
Small-scale |
0.578 | High |
|
|
EP300
Histone acetyltransferase p300 |
1 |
20 |
Small-scale |
0.578 | High |
|
|
TGFI1
Transforming growth factor beta-1-induced transcript 1 protein |
1 |
12 |
Small-scale |
0.561 | High |
|
|
CBL
E3 ubiquitin-protein ligase CBL |
1 |
7 |
Small-scale |
0.561 | High |
|
|
ZEB1
Zinc finger E-box-binding homeobox 1 |
1 |
20 |
Small-scale |
0.561 | High |
|
|
SIR1
NAD-dependent protein deacetylase sirtuin-1 |
1 |
1 |
Small-scale |
0.561 | High |
|
|
UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5 |
1 |
7 |
Small-scale |
0.561 | High |
|
|
STABP
STAM-binding protein |
1 |
3 |
Small-scale |
0.552 | High |
|
|
FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A |
1 |
1 |
Small-scale |
0.543 | High |
|
|
ANM7
Protein arginine N-methyltransferase 7 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 |
1 |
4 |
Small-scale |
0.529 | High |
|
|
PR15A
Protein phosphatase 1 regulatory subunit 15A |
1 |
0 |
Small-scale |
0.529 | High |
|
|
M3K7
Mitogen-activated protein kinase kinase kinase 7 |
1 |
9 |
Small-scale |
0.515 | High |
|
|
TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 |
1 |
3 |
Small-scale |
0.515 | High |
|
|
PSMG1
Proteasome assembly chaperone 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
VNN1
Pantetheinase |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PSMG2
Proteasome assembly chaperone 2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
DCA16
DDB1- and CUL4-associated factor 16 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PIAS1
E3 SUMO-protein ligase PIAS1 |
1 |
16 |
High-throughput |
0.508 | High |
|
|
ZBT11
Zinc finger and BTB domain-containing protein 11 |
1 |
4 |
High-throughput |
0.508 | High |
|
|
XRCC6
X-ray repair cross-complementing protein 6 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
MYOD1
Myoblast determination protein 1 |
1 |
4 |
High-throughput |
0.508 | High |
|
|
SOX5
Transcription factor SOX-5 |
1 |
20 |
High-throughput |
0.508 | High |
|
|
TTF1
Transcription termination factor 1 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
CXXC5
CXXC-type zinc finger protein 5 |
1 |
3 |
High-throughput |
0.508 | High |
|
|
SOX7
Transcription factor SOX-7 |
1 |
14 |
High-throughput |
0.508 | High |
|
|
HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein |
1 |
6 |
High-throughput |
0.508 | High |
|
|
ASH1L
Histone-lysine N-methyltransferase ASH1L |
1 |
11 |
High-throughput |
0.508 | High |
|
|
ZN107
Zinc finger protein 107 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
MRTFB
Myocardin-related transcription factor B |
1 |
7 |
High-throughput |
0.508 | High |
|
|
SOX13
Transcription factor SOX-13 |
1 |
20 |
High-throughput |
0.508 | High |
|
|
TTF2
Transcription termination factor 2 |
1 |
5 |
High-throughput |
0.508 | High |
|
|
KDM2A
Lysine-specific demethylase 2A |
1 |
3 |
High-throughput |
0.508 | High |
|
|
DVL1
Segment polarity protein dishevelled homolog DVL-1 |
1 |
16 |
Small-scale |
0.501 | High |
|
|
PARD3
Partitioning defective 3 homolog |
1 |
7 |
Small-scale |
0.501 | High |
|
|
SETD7
Histone-lysine N-methyltransferase SETD7 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
ERBIN
Erbin |
1 |
10 |
Small-scale |
0.501 | High |
|
|
ANM5
Protein arginine N-methyltransferase 5 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
OVOL1
Putative transcription factor Ovo-like 1 |
1 |
10 |
Small-scale |
0.479 | High |
|
|
MED24
Mediator of RNA polymerase II transcription subunit 24 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
TRI37
E3 ubiquitin-protein ligase TRIM37 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
MYC
Myc proto-oncogene protein |
1 |
11 |
Small-scale |
0.479 | High |
|
|
P53
Cellular tumor antigen p53 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
PAI1
Plasminogen activator inhibitor 1 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
SRF
Serum response factor |
1 |
3 |
Small-scale |
0.479 | High |
|
|
CADH1
Cadherin-1 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
EGR1
Early growth response protein 1 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1 |
1 |
12 |
Small-scale |
0.479 | High |
|
|
AKT1
RAC-alpha serine/threonine-protein kinase |
1 |
9 |
Small-scale |
0.479 | High |
|
|
MP2K3
Dual specificity mitogen-activated protein kinase kinase 3 |
1 |
17 |
Small-scale |
0.479 | High |
|
|
MP2K6
Dual specificity mitogen-activated protein kinase kinase 6 |
1 |
17 |
Small-scale |
0.479 | High |
|
|
ACVR1
Activin receptor type-1 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
BAMBI
BMP and activin membrane-bound inhibitor homolog |
1 |
1 |
Small-scale |
0.479 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
ATM
Serine-protein kinase ATM |
1 |
2 |
Small-scale |
0.479 | High |
|
|
CUL4A
Cullin-4A |
1 |
7 |
High-throughput |
0.479 | High |
|
|
CUL4B
Cullin-4B |
1 |
7 |
High-throughput |
0.479 | High |
|
|
AVR2B
Activin receptor type-2B |
1 |
20 |
Small-scale |
0.479 | High |
|
|
BMPR2
Bone morphogenetic protein receptor type-2 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
HERC3
Probable E3 ubiquitin-protein ligase HERC3 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
T22D1
TSC22 domain family protein 1 |
1 |
15 |
Small-scale |
0.479 | High |
|
|
TBR1
T-box brain protein 1 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
ARK2C
E3 ubiquitin-protein ligase ARK2C |
1 |
10 |
Small-scale |
0.479 | High |
|
|
KAT2B
Histone acetyltransferase KAT2B |
1 |
13 |
Small-scale |
0.479 | High |
|
|
STALP
AMSH-like protease |
1 |
3 |
Small-scale |
0.479 | High |
|
|
OVOL2
Transcription factor Ovo-like 2 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
UBP26
Ubiquitin carboxyl-terminal hydrolase 26 |
1 |
16 |
Small-scale |
0.479 | High |
|
|
TBL1R
F-box-like/WD repeat-containing protein TBL1XR1 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme |
1 |
2 |
Small-scale |
0.479 | High |
|
|
TF7L2
Transcription factor 7-like 2 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
PSME3
Proteasome activator complex subunit 3 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TOLIP
Toll-interacting protein |
1 |
0 |
Small-scale |
0.458 | High |
|
|
UB2L3
Ubiquitin-conjugating enzyme E2 L3 |
1 |
1 |
Small-scale |
0.408 | High |
|
|
CHIT1
Chitotriosidase-1 |
1 |
0 |
High-throughput |
0.279 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
