HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	21331078, 23313255
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 671
+	Hs
		1038344 UBP15_HUMAN (1-924): 0: 749: 58.17		RIPK1_HUMAN (1-671): 0: 610: 100.00
+	Hs
		201321 UBP4_HUMAN (1-963): 0: 908: 100.00		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		201481 UBP15_HUMAN (1-924): 0: 749: 58.17		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		1038339 UBP20_HUMAN (203-962): 3.45e-110: 363: 17.72		RIPK1_HUMAN (1-671): 0: 610: 100.00
+	Hs
		201151 UBP19_HUMAN (183-937): 6.87e-148: 474: 30.87		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		271088 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		RIPK1_HUMAN (1-671): 0: 610: 100.00
+	Hs
		1038334 UBP21_HUMAN (651-928): 3.71e-63: 226: 25.00		RIPK1_HUMAN (1-671): 0: 610: 100.00
+	Hs
		411649 UBP11_HUMAN (6-937): 0: 717: 44.60		LCK_HUMAN (23-289): 1.31e-27: 119: 31.87
+	Hs
		201251 UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		201145 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		M3K7_HUMAN (4-611): 9.44e-125: 384: 19.18
+	Hs
		433847 UBP31_HUMAN (484-741): 2.35e-14: 80: 8.45		LYN_HUMAN (23-289): 6.17e-28: 120: 32.13