HitPredict

Interactor 1: PAX2 (Q02962)
Paired box protein Pax-2
Gene: PAX2

Interactor 2: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	10908331, 35140242
Identification Methods	affinity chromatography technology, two hybrid, pull down, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 1069
+	Mm
		732245 PAX2_MOUSE (1-417): 2.94e-119: 355: 98.32		PAXI1_MOUSE (592-1069): 8.7e-145: 462: 92.47
+	Mm
		1038083 PAX5_MOUSE (1-417): 2e-100: 306: 63.40		PAXI1_MOUSE (592-1069): 8.7e-145: 462: 92.47
+	Mm
		989227 PAX6_MOUSE (13-417): 3.99e-93: 288: 33.01		PAXI1_MOUSE (592-1069): 8.7e-145: 462: 92.47
+	Mm
		1024324 PAX8_MOUSE (9-415): 7.1e-74: 239: 48.22		PAXI1_MOUSE (592-1069): 8.7e-145: 462: 92.47
+	Hs
		685244 PAX6_HUMAN (13-417): 3.99e-93: 288: 33.01		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		662241 PAX7_HUMAN (16-410): 8.34e-82: 261: 31.33		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		1056619 PAX8_HUMAN (9-415): 7.55e-74: 239: 47.98		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		938464 PAX9_HUMAN (13-250): 4.87e-55: 187: 44.77		PAXI1_HUMAN (1-419): 3.12e-90: 314: 100.00
+	Hs
		1040086 PAX2_HUMAN (1-417): 1.67e-121: 360: 100.00		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1040063 PAX2_HUMAN (1-417): 1.67e-121: 360: 100.00		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		685368 PAX6_HUMAN (13-417): 3.99e-93: 288: 33.01		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		662289 PAX7_HUMAN (16-410): 8.34e-82: 261: 31.33		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1056658 PAX8_HUMAN (9-415): 7.55e-74: 239: 47.98		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		685267 PAX6_HUMAN (13-417): 3.99e-93: 288: 33.01		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		662249 PAX7_HUMAN (16-410): 8.34e-82: 261: 31.33		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		938513 PAX9_HUMAN (13-250): 4.87e-55: 187: 44.77		CHD7_HUMAN (188-893): 5.78e-32: 138: 8.81
+	Hs
		1056627 PAX8_HUMAN (9-415): 7.55e-74: 239: 47.98		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07
+	Hs
		938480 PAX9_HUMAN (13-250): 4.87e-55: 187: 44.77		KMT2C_HUMAN (162-646): 4.44e-10: 66.6: 10.07