HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	19112176
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 589
+	Hs
		1025999 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		852196 ROA3_HUMAN (98-269): 2.33e-69: 225: 28.57		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Dm
		1375071 Q9W1I0_DROME (4-323): 2.53e-60: 200: 50.00		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		1031489 PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		680496 TIA1_HUMAN (99-413): 2.4e-38: 144: 13.76		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		516729 PABP1_HUMAN (2-382): 7.78e-31: 126: 15.95		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		1025833 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		UBQLN_HUMAN (33-453): 5.18e-74: 245: 33.48
+	Hs
		1025782 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		803509 TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Dm
		1248850 Q8SXP8_DROME (3-389): 1.44e-71: 235: 44.58		Q9V3W9_DROME (37-394): 1.42e-40: 154: 13.95
+	Dm
		1359308 Q9W1I0_DROME (4-323): 2.53e-60: 200: 50.00		Q9V3W9_DROME (37-394): 1.42e-40: 154: 13.95
+	Hs
		803528 HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66