HitPredict

Interactor 1: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Interactor 2: PHOCN (Q9Y3A3)
MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)
Gene: MOB4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	32707033, 19797269, 24255178
Identification Methods	affinity chromatography technology, enzymatic study, proximity labelling technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 491 Hs			1 225
+	Hs
		1027394 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MOB3B_HUMAN (20-212): 5.12e-91: 268: 20.40
+	Hs
		1023145 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1027437 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MOB1A_HUMAN (17-212): 4.06e-89: 263: 20.10
+	Hs
		1027391 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MOB1B_HUMAN (19-212): 8.58e-88: 259: 20.30
+	Hs
		1023117 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MOB1A_HUMAN (17-212): 4.06e-89: 263: 20.10
+	Hs
		1023070 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MOB1B_HUMAN (19-212): 8.58e-88: 259: 20.30
+	Hs
		1377585 STK24_HUMAN (16-325): 6.03e-124: 370: 50.32		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		131625 STK25_HUMAN (9-426): 4.69e-123: 368: 40.28		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Dm
		1178607 Q9VEN3_DROME (22-323): 1.36e-124: 379: 50.49		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Hs
		1350187 STK26_HUMAN (22-392): 4.24e-122: 364: 44.27		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1350192 STK26_HUMAN (22-392): 4.24e-122: 364: 44.27		S4R3N1_HUMAN (14-225): 1.29e-103: 301: 97.64
+	Hs
		1026924 PAK2_HUMAN (6-302): 2.65e-119: 361: 41.04		MOB3C_HUMAN (19-217): 1.08e-87: 259: 17.87
+	Mm
		949324 TNIK_MOUSE (6-303): 2.2e-70: 245: 44.03		PHOCN_MOUSE (1-225): 8.34e-111: 318: 100.00
+	Hs
		1233571 MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1356420 TNIK_HUMAN (6-303): 4.21e-70: 244: 44.03		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Dm
		1178592 Q7KV89_DROME (21-320): 2.82e-70: 244: 42.54		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Dm
		56110 A1ZBH7_DROME (14-293): 1.86e-76: 262: 45.99		MOB1_DROME (22-212): 2.97e-86: 256: 21.68
+	Hs
		1198329 MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43		MOB3B_HUMAN (20-212): 5.12e-91: 268: 20.40
+	Hs
		1174260 MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43		MOB3C_HUMAN (19-217): 1.08e-87: 259: 17.87
+	Dm
		1178598 HIPPO_DROME (433-490): 1.74e-22: 102: 55.17		MOB4_DROME (1-225): 1.36e-105: 305: 80.00