HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: DDI1 (Q8WTU0)
Protein DDI1 homolog 1 (EC 3.4.23.-)
Gene: DDI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 908 Hs			1 396
+	Hs
		1027692 PSMD2_HUMAN (1-908): 0: 1290: 100.00		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		1027821 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		1027815 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		1027806 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Hs
		923974 PSMD2_HUMAN (1-908): 0: 1290: 100.00		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Hs
		1259550 PSMD1_HUMAN (59-845): 0: 790: 17.31		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		1136649 PSMD1_HUMAN (59-845): 0: 790: 17.31		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Dm
		1374998 Q9VW54_DROME (3-906): 0: 1063: 60.65		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Dm
		1362832 Q9VW54_DROME (3-906): 0: 1063: 60.65		Q9VCD5_DROME (5-218): 1.23e-30: 120: 18.92
+	Sc
		753827 RPN1_YEAST (49-906): 0: 869: 37.71		DDI1_YEAST (14-369): 1.01e-91: 284: 29.41
+	Sp
		953205 RPN1_SCHPO (8-905): 0: 1025: 47.67		DSK2_SCHPO (2-187): 4.47e-28: 114: 13.08
+	Sc
		753873 RPN1_YEAST (49-906): 0: 869: 37.71		DSK2_YEAST (14-202): 5.04e-25: 106: 17.84
+	Hs
		1303954 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		1303948 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		1303937 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Hs
		924124 PSMD1_HUMAN (59-845): 0: 790: 17.31		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Dm
		1359018 PSMD1_DROME (59-845): 0: 710: 17.07		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55