HitPredict

Interactor 1: DEF5 (Q01523)
Defensin alpha 5 (Defensin-5) (HD5(20-94)) [Cleaved into: HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94)]
Gene: DEFA5

Interactor 2: LTBP1 (Q14766)
Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)
Gene: LTBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 1721
+	Hs
		1030780 DEF5_HUMAN (1-94): 6.6e-36: 118: 100.00		LTBP2_HUMAN (1255-1721): 7.77e-25: 115: 17.41
+	Hs
		948030 DEF1_HUMAN (1-93): 1.29e-40: 130: 48.94		NOTC3_HUMAN (117-842): 8.58e-16: 86: 7.79
+	Hs
		654485 DEF1_HUMAN (1-93): 1.29e-40: 130: 48.94		FBLN1_HUMAN (1204-1506): 2.33e-14: 80.5: 27.56
+	Hs
		1030797 DEF5_HUMAN (1-94): 6.6e-36: 118: 100.00		FRAS1_HUMAN (1290-1720): 1.67e-09: 65.4: 9.93