Interactor 1: SPE4 (Q01608)
Presenilin spe-4
Gene: spe-4

Interactor 2: SPE4 (Q01608)
Presenilin spe-4
Gene: spe-4

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 29546388
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Presenilin~Presenilin
Common GO terms GO:0004175 - endopeptidase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0006509 - membrane protein ectodomain proteolysis
GO:0006996 - organelle organization
and 11 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 465
Ce

1 465
+ Dm
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 11Aug2025