HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34978798
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 325 Hs			1 759
+	Hs
		903208 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1032085 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1043085 WDR5B_HUMAN (180-325): 2.45e-34: 129: 13.61		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043064 BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043157 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		903209 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		792982 LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043441 WDR5B_HUMAN (180-325): 2.45e-34: 129: 13.61		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043417 BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043114 POC1B_HUMAN (226-325): 7.26e-14: 73.9: 21.78		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043509 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043469 POC1B_HUMAN (226-325): 7.26e-14: 73.9: 21.78		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043499 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		197016 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903207 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042101 POC1B_HUMAN (226-325): 7.26e-14: 73.9: 21.78		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903206 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1042903 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Mm
		1257398 FBXW7_MOUSE (5-75): 2.93e-09: 60: 24.05		CUL1_MOUSE (59-759): 0: 745: 30.55
+	Hs
		1041133 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		CUL1_HUMAN (59-759): 0: 745: 30.55