HitPredict

Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 347
+	Hs
		1033633 IKZF1_HUMAN (1-519): 0: 664: 100.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		880715 IKZF1_HUMAN (1-519): 0: 664: 100.00		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		1033690 IKZF1_HUMAN (1-519): 0: 664: 100.00		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177285 IKZF1_HUMAN (1-519): 0: 664: 100.00		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		1033686 IKZF1_HUMAN (1-519): 0: 664: 100.00		HDAC7_HUMAN (13-344): 1.91e-121: 373: 19.89
+	Hs
		1038804 IKZF2_HUMAN (37-517): 1.17e-145: 430: 53.74		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		880848 IKZF2_HUMAN (37-517): 1.17e-145: 430: 53.74		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		1038805 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		880822 IKZF4_HUMAN (28-515): 2.23e-142: 423: 51.26		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		1270517 IKZF2_HUMAN (37-517): 1.17e-145: 430: 53.74		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		880849 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		1270436 IKZF4_HUMAN (28-515): 2.23e-142: 423: 51.26		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		1260190 IKZF4_HUMAN (28-515): 2.23e-142: 423: 51.26		HDAC7_HUMAN (13-344): 1.91e-121: 373: 19.89
+	Hs
		1270518 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		1260200 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		HDAC7_HUMAN (13-344): 1.91e-121: 373: 19.89
+	Mm
		140300 Q8C5P6_MOUSE (1-254): 8.48e-111: 331: 94.88		HDAC1_MOUSE (13-330): 6.68e-140: 407: 22.89
+	Mm
		936415 Q8C5P6_MOUSE (1-254): 8.48e-111: 331: 94.88		HDAC2_MOUSE (13-330): 6.36e-128: 376: 22.59
+	Hs
		1193248 ZSCA2_HUMAN (277-519): 8.68e-36: 142: 13.17		HDAC8_HUMAN (19-310): 9.6e-14: 73.6: 25.97