Interactor 1: TOP3A (Q13472)
DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha)
Gene: TOP3A

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 24699063, 20064461, 16116422
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Toprim
Common GO terms GO:0005654 - nucleoplasm
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1001
Hs

1 2048
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024