HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: STX8 (Q9UNK0)
Syntaxin-8
Gene: STX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	35271311, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 236
+	Hs
		235153 NSF_HUMAN (1-744): 0: 572: 100.00		STX10_HUMAN (3-221): 2.24e-51: 168: 17.39
+	Hs
		212755 NSF_HUMAN (1-744): 0: 572: 100.00		STX6_HUMAN (3-221): 2.26e-43: 148: 17.30
+	Hs
		320275 NSF_HUMAN (1-744): 0: 572: 100.00		SNP29_HUMAN (10-207): 2.95e-28: 109: 20.50
+	Hs
		169401 NSF_HUMAN (1-744): 0: 572: 100.00		BET1_HUMAN (149-234): 6.31e-25: 96.8: 18.61
+	Dm
		870085 NSF2_DROME (5-742): 6.55e-166: 498: 63.21		Q9VV76_DROME (4-223): 7.2e-43: 146: 24.32
+	Dm
		870086 NSF2_DROME (5-742): 6.55e-166: 498: 63.21		Q9VVX6_DROME (161-234): 4.68e-13: 65.7: 20.00
+	Sc
		578521 SEC18_YEAST (4-721): 5.88e-146: 447: 44.22		VAM7_YEAST (46-211): 1.29e-25: 103: 21.56
+	Sc
		578503 SEC18_YEAST (4-721): 5.88e-146: 447: 44.22		BET1_YEAST (93-235): 4.89e-27: 102: 18.06
+	Zm
		86554 K7VQA7_MAIZE (13-483): 1.02e-72: 254: 23.44		C4J0R0_MAIZE (120-231): 1.27e-25: 98.8: 18.97