HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 1140
+	Hs
		1036960 SQSTM_HUMAN (1-440): 0: 760: 100.00		DAPLE_HUMAN (100-794): 4.47e-11: 69.7: 13.99
+	Hs
		1145819 MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		319877 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		1056044 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		319864 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61
+	Mm
		1118137 HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50		MYH10_MOUSE (410-1140): 4.04e-40: 164: 13.68
+	Dm
		1303397 Q9VJ14_DROME (108-231): 3.23e-23: 104: 25.40		MYSN_DROME (222-1110): 3.36e-27: 122: 13.91
+	Hs
		551704 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86