Protein: APBA2
Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2)

Gene: APBA2
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q99767

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001701 - in utero embryonic development
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

422974

A4
Amyloid-beta precursor protein

6

19

Small-scale

0.944

High

1036681

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

3

19

High-throughput

0.855

High

1407284

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

6

4

High-throughput

0.734

High

1055349

APLP2
Amyloid beta precursor like protein 2

2

11

High-throughput

0.726

High

324031

CSTN1
Calsyntenin-1

4

13

Small-scale

0.692

High

1206649

TJAP1
Tight junction-associated protein 1

3

9

High-throughput

0.662

High

1207206

IQEC2
IQ motif and SEC7 domain-containing protein 2

3

7

High-throughput

0.662

High

1407276

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

17

Small-scale

0.647

High

343028

HERC2
E3 ubiquitin-protein ligase HERC2

2

9

High-throughput

0.628

High

1066246

DMWD
Dystrophia myotonica WD repeat-containing protein

2

4

High-throughput

0.628

High

1353415

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

2

4

High-throughput

0.628

High

1407283

FBW1A
F-box/WD repeat-containing protein 1A

2

4

High-throughput

0.628

High

1255233

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

1399518

NECA3
N-terminal EF-hand calcium-binding protein 3

2

4

Small-scale

0.611

High

1231870

IQEC1
IQ motif and SEC7 domain-containing protein 1

3

7

High-throughput

0.604

High

1243896

AAGAB
Alpha- and gamma-adaptin-binding protein p34

2

0

High-throughput

0.602

High

190470

COPT1
High affinity copper uptake protein 1

2

2

High-throughput

0.601

High

1230730

Z518A
Zinc finger protein 518A

2

1

High-throughput

0.574

High

1407282

FBW1B
F-box/WD repeat-containing protein 11

2

4

High-throughput

0.574

High

963460

STXB1
Syntaxin-binding protein 1

2

6

Small-scale

0.571

High

1045696

TF65
Transcription factor p65

1

3

Small-scale

0.552

High

943615

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

5

High-throughput

0.541

High

1331845

SYT2
Synaptotagmin-2

1

2

High-throughput

0.536

High

1407277

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.536

High

958812

ARF3
ADP-ribosylation factor 3

1

11

Small-scale

0.527

High

1103791

PLD1
Phospholipase D1

1

0

High-throughput

0.513

High

1161198

MK06
Mitogen-activated protein kinase 6

1

9

High-throughput

0.508

High

158920

CCS
Copper chaperone for superoxide dismutase

1

3

Small-scale

0.501

High

890042

PSN1
Presenilin-1

1

4

Small-scale

0.501

High

1028118

CAC1B
Voltage-dependent N-type calcium channel subunit alpha-1B

1

5

Small-scale

0.501

High

66809

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

2

High-throughput

0.489

High

1357733

TRI41
E3 ubiquitin-protein ligase TRIM41

1

4

High-throughput

0.489

High

1407279

RNF12
E3 ubiquitin-protein ligase RLIM

1

5

High-throughput

0.489

High

612291

ARF4
ADP-ribosylation factor 4

1

11

Small-scale

0.481

High

1022642

LRP2
Low-density lipoprotein receptor-related protein 2

1

12

Small-scale

0.481

High

1060908

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

12

Small-scale

0.481

High

1120580

LRP8
Low-density lipoprotein receptor-related protein 8

1

12

Small-scale

0.481

High

180028

BET1
BET1 homolog

1

3

High-throughput

0.479

High

315936

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

613158

EGR1
Early growth response protein 1

1

3

High-throughput

0.479

High

890772

PSN2
Presenilin-2

1

4

Small-scale

0.479

High

1229054

RNF43
E3 ubiquitin-protein ligase RNF43

1

5

High-throughput

0.479

High

1110547

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

20

High-throughput

0.445

High

1306885

INLR1
Interferon lambda receptor 1

1

1

High-throughput

0.445

High

1407280

SL9A2
Sodium/hydrogen exchanger 2

1

1

High-throughput

0.445

High

1407278

SP110
Sp110 nuclear body protein

1

3

High-throughput

0.437

High

1141470

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

1

High-throughput

0.407

High

1149018

SC23B
Protein transport protein Sec23B

1

1

High-throughput

0.407

High

1407281

APEX2
DNA-(apurinic or apyrimidinic site) endonuclease 2

3

0

High-throughput

0.346

High

62155

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

0

High-throughput

0.328

High

1330710

MAGB6
Melanoma-associated antigen B6

2

0

High-throughput

0.316

High

1219465

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

1276289

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025