Protein: BEGIN
Brain-enriched guanylate kinase-associated protein

Gene: BEGIN, BEGAIN
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9BUH8

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0016020 - membrane
GO:0045202 - synapse
GO:0098794 - postsynapse
GO:0098817 - evoked excitatory postsynaptic potential

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

262428

DTNB
Dystrobrevin beta

3

0

High-throughput

0.639

High

1239200

ZN774
Zinc finger protein 774

3

2

High-throughput

0.616

High

1295614

RASL3
RAS protein activator like-3

2

1

High-throughput

0.606

High

1414258

TRAF4
TNF receptor-associated factor 4

2

1

High-throughput

0.606

High

1328061

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

3

1

High-throughput

0.597

High

684375

DDX6
Probable ATP-dependent RNA helicase DDX6

2

0

High-throughput

0.580

High

715949

AQP1
Aquaporin-1

2

0

High-throughput

0.580

High

941052

HDAC4
Histone deacetylase 4

2

0

High-throughput

0.580

High

1347720

ZN417
Zinc finger protein 417

2

1

High-throughput

0.573

High

1396572

C170L
Cep170-like protein

3

1

High-throughput

0.569

High

1210975

CE170
Centrosomal protein of 170 kDa

2

2

High-throughput

0.558

High

1213251

ZN648
Zinc finger protein 648

2

1

High-throughput

0.553

High

1277123

ZN572
Zinc finger protein 572

2

1

High-throughput

0.553

High

1402938

ZN587
Zinc finger protein 587

2

1

High-throughput

0.553

High

1414265

CDC23
Cell division cycle protein 23 homolog

2

1

High-throughput

0.553

High

159259

ABLM1
Actin-binding LIM protein 1

1

1

High-throughput

0.541

High

1006099

DLG4
Disks large homolog 4

1

6

High-throughput

0.541

High

288497

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

High-throughput

0.518

High

352796

F107A
Actin-associated protein FAM107A

1

0

High-throughput

0.518

High

572176

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.518

High

1308388

HID1
Protein HID1

1

0

High-throughput

0.518

High

1414261

DEFI6
Differentially expressed in FDCP 6 homolog

1

0

High-throughput

0.518

High

292732

RENR
Renin receptor

1

0

High-throughput

0.513

High

1051303

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

1217761

GFI1B
Zinc finger protein Gfi-1b

1

1

High-throughput

0.494

High

1386556

OPTN
Optineurin

1

0

High-throughput

0.493

High

1413263

TCHP
Trichoplein keratin filament-binding protein

1

0

High-throughput

0.493

High

423040

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

173296

XPO1
Exportin-1

1

2

High-throughput

0.479

High

1388966

ZN837
Zinc finger protein 837

1

1

High-throughput

0.470

High

1096383

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

0

High-throughput

0.458

High

1414257

BEGIN
Brain-enriched guanylate kinase-associated protein

1

0

Small-scale

0.458

High

1414263

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.438

High

1414260

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.327

High

506766

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

611749

BMP7
Bone morphogenetic protein 7

2

0

High-throughput

0.316

High

933886

GEM
GTP-binding protein GEM

2

0

High-throughput

0.316

High

1185314

F161A
Protein FAM161A

2

0

High-throughput

0.316

High

1295099

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1315742

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.316

High

1331428

MB213
Protein mab-21-like 3

2

0

High-throughput

0.316

High

1385253

LENG1
Leukocyte receptor cluster member 1

2

0

High-throughput

0.316

High

1394258

GMCL1
Germ cell-less protein-like 1

2

0

High-throughput

0.316

High

1399219

GUCD1
Protein GUCD1

2

0

High-throughput

0.316

High

1406147

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

1414259

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.316

High

1414264

ZN319
Zinc finger protein 319

2

0

High-throughput

0.316

High

1414266

ZN835
Zinc finger protein 835

2

0

High-throughput

0.316

High

1410516

KXDL1
KxDL motif-containing protein 1

2

0

High-throughput

0.313

High

704989

RBL1
Retinoblastoma-like protein 1

1

0

High-throughput

0.304

High

133199

QSOX1
Sulfhydryl oxidase 1

1

0

High-throughput

0.282

High

169733

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

High-throughput

0.282

High

585093

ZN250
Zinc finger protein 250

1

0

High-throughput

0.282

High

1256461

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.282

High

1337337

CTSR1
Cation channel sperm-associated protein 1

1

0

High-throughput

0.282

High

1348748

BAHD1
Bromo adjacent homology domain-containing 1 protein

1

0

High-throughput

0.282

High

1414262

RIBC2
RIB43A-like with coiled-coils protein 2

1

0

High-throughput

0.282

High

1384512

SKA1
SKA complex subunit 1

1

0

High-throughput

0.279

Low

1185181

GFOD2
Glucose-fructose oxidoreductase domain-containing protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025