HitPredict

Interactor 1: PRP4K (Q13523)
Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)
Gene: PRP4K

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1007 Hs			1 726
+	Hs
		631422 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		998665 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		244397 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		408701 KPCB_HUMAN (486-990): 2.48e-122: 390: 15.01		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		999150 CDK12_HUMAN (31-1005): 5.97e-121: 405: 15.92		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		625449 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		ZMY11_HUMAN (3-446): 1.03e-44: 171: 9.63
+	Hs
		566375 KPCA_HUMAN (486-978): 6.58e-123: 391: 15.94		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		408611 KPCB_HUMAN (486-990): 2.48e-122: 390: 15.01		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		414892 CDK1_HUMAN (684-1005): 4.59e-124: 381: 25.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		999248 DYR1B_HUMAN (618-1005): 4.81e-119: 380: 30.25		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		625393 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		625533 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86
+	Sc
		565752 PHO85_YEAST (686-1005): 4.97e-117: 363: 27.74		GCN5_YEAST (284-417): 7.13e-37: 145: 31.88
+	Hs
		625534 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50
+	Hs
		245029 CDK12_HUMAN (31-1005): 5.97e-121: 405: 15.92		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		243796 CDK1_HUMAN (684-1005): 4.59e-124: 381: 25.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Sc
		565790 PHO85_YEAST (686-1005): 4.97e-117: 363: 27.74		BDF2_YEAST (250-500): 3e-24: 110: 20.32
+	Hs
		243949 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244291 CDK5_HUMAN (684-1005): 2.54e-117: 363: 26.14		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Sc
		339866 CDK1_YEAST (686-1005): 2.59e-111: 347: 28.27		BDF2_YEAST (250-500): 3e-24: 110: 20.32