HitPredict

Interactor 1: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Interactor 2: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17785777, 21398614
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response GO:0045893 - positive regulation of DNA-templated transcription GO:0051607 - defense response to virus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 503
+	Hs
		1316503 IFNL3_HUMAN (1-191): 5.17e-117: 331: 71.94		IRF7_HUMAN (1-503): 0: 530: 100.00
+	Hs
		1037803 IFNL1_HUMAN (1-200): 1.34e-123: 348: 100.00		IRF8_HUMAN (12-485): 3.84e-123: 368: 21.04
+	Hs
		1037804 IFNL3_HUMAN (1-191): 5.17e-117: 331: 71.94		IRF8_HUMAN (12-485): 3.84e-123: 368: 21.04
+	Hs
		533947 IFNL1_HUMAN (1-200): 1.34e-123: 348: 100.00		IRF1_HUMAN (8-276): 4.25e-71: 230: 19.00
+	Hs
		533951 IFNL3_HUMAN (1-191): 5.17e-117: 331: 71.94		IRF1_HUMAN (8-276): 4.25e-71: 230: 19.00
+	Hs
		1129157 IFNL1_HUMAN (1-200): 1.34e-123: 348: 100.00		IRF3_HUMAN (6-263): 1.1e-60: 207: 25.66
+	Hs
		1129160 IFNL3_HUMAN (1-191): 5.17e-117: 331: 71.94		IRF3_HUMAN (6-263): 1.1e-60: 207: 25.66