HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0051059 - NF-kappaB binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 1128
+	Hs
		518865 HDAC1_HUMAN (1-482): 0: 668: 100.00		TPR_HUMAN (62-894): 9.75e-55: 211: 13.79
+	Hs
		1260086 HDAC2_HUMAN (1-478): 0: 666: 85.92		IASPP_HUMAN (416-1127): 1.13e-53: 204: 21.65
+	Hs
		166921 HDAC1_HUMAN (1-482): 0: 668: 100.00		ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78
+	Hs
		1219802 HDAC2_HUMAN (1-478): 0: 666: 85.92		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		1038631 HDAC1_HUMAN (1-482): 0: 668: 100.00		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1270381 HDAC2_HUMAN (1-478): 0: 666: 85.92		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1260177 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		PP16A_HUMAN (939-1037): 6.43e-21: 99: 33.33
+	Hs
		161415 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		161469 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89