HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: TGIF2 (Q9GZN2)
Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGF-beta-induced transcription factor 2) (TGFB-induced factor 2)
Gene: TGIF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11427533
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 237
+	Hs
		1038406 HDAC1_HUMAN (1-482): 0: 668: 100.00		TGIF1_HUMAN (13-219): 2.49e-41: 147: 48.97
+	Hs
		1038509 HDAC1_HUMAN (1-482): 0: 668: 100.00		TF2LX_HUMAN (1-222): 3.79e-38: 134: 40.44
+	Hs
		1216204 HDAC2_HUMAN (1-478): 0: 666: 85.92		TF2LX_HUMAN (1-222): 3.79e-38: 134: 40.44
+	Hs
		147202 HDAC1_HUMAN (1-482): 0: 668: 100.00		CUX2_HUMAN (3-226): 1.72e-34: 132: 18.75
+	Hs
		773070 HDAC1_HUMAN (1-482): 0: 668: 100.00		PBX1_HUMAN (19-187): 1.52e-33: 127: 20.31
+	Hs
		177218 HDAC3_HUMAN (9-434): 0: 574: 57.94		PBX1_HUMAN (19-187): 1.52e-33: 127: 20.31