Protein: BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC 2.7.11.1)

Gene: BCK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 162
UniProt ID: Q01389

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000196 - cell integrity MAPK cascade
GO:0000425 - pexophagy
GO:0004672 - protein kinase activity
GO:0004709 - MAP kinase kinase kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1027257

SLT2
Mitogen-activated protein kinase SLT2/MPK1

5

20

Small-scale

0.929

High

738072

MKK2
MAP kinase kinase MKK2/SSP33

3

16

Small-scale

0.870

High

738042

MKK1
MAP kinase kinase MKK1/SSP32

3

16

Small-scale

0.857

High

763234

PP2C1
Protein phosphatase 2C homolog 1

2

12

High-throughput

0.793

High

1030255

RRP5
rRNA biogenesis protein RRP5

2

2

High-throughput

0.714

High

1030268

NBP2
NAP1-binding protein 2

5

2

Small-scale

0.708

High

623000

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.691

High

778965

KDX1
Serine/threonine-protein kinase KDX1

1

20

High-throughput

0.691

High

801897

KSP1
Serine/threonine-protein kinase KSP1

1

18

High-throughput

0.691

High

1026800

CDC14
Tyrosine-protein phosphatase CDC14

1

4

High-throughput

0.691

High

1030243

PKH3
Serine/threonine-protein kinase PKH3

1

17

High-throughput

0.691

High

1030270

GIN4
Serine/threonine-protein kinase GIN4

1

17

High-throughput

0.691

High

779012

MYO3
Myosin-3

3

16

High-throughput

0.680

High

1030252

MYO5
Myosin-5

3

13

High-throughput

0.674

High

574599

YAK1
Dual specificity protein kinase YAK1

1

17

High-throughput

0.647

High

628086

FKBP
FK506-binding protein 1

1

10

High-throughput

0.647

High

665847

KPC1
Protein kinase C-like 1

1

17

Small-scale

0.647

High

694161

CDC15
Cell division control protein 15

1

17

High-throughput

0.647

High

778950

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

16

High-throughput

0.647

High

865957

DPH4
Diphthamide biosynthesis protein 4

1

17

High-throughput

0.647

High

924990

APJ1
J domain-containing protein APJ1

1

16

High-throughput

0.647

High

1030266

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

3

High-throughput

0.647

High

1030267

RTK1
Probable serine/threonine-protein kinase RTK1

1

18

High-throughput

0.647

High

1030272

OSH2
Oxysterol-binding protein homolog 2

1

2

High-throughput

0.647

High

364694

CDK1
Cyclin-dependent kinase 1

1

8

High-throughput

0.621

High

1030240

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

15

Small-scale

0.621

High

746657

DRS1
ATP-dependent RNA helicase DRS1

2

3

High-throughput

0.619

High

791091

NOP4
Nucleolar protein 4

1

8

High-throughput

0.618

High

807124

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

10

High-throughput

0.618

High

924312

NOP13
Nucleolar protein 13

1

6

High-throughput

0.618

High

1030261

NOP12
Nucleolar protein 12

1

9

High-throughput

0.618

High

865928

BUD4
Bud site selection protein 4

1

0

High-throughput

0.614

High

1030277

RGS2
Regulator of G-protein signaling 2

1

0

High-throughput

0.614

High

670323

NAP1
Nucleosome assembly protein

2

1

High-throughput

0.611

High

819530

SSB2
Ribosome-associated molecular chaperone SSB2

2

20

High-throughput

0.588

High

849835

BUD27
Bud site selection protein 27

2

0

High-throughput

0.577

High

393186

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

676268

MAS5
Mitochondrial protein import protein MAS5

1

14

High-throughput

0.575

High

1030249

GIS1
Transcriptional activator/repressor GIS1

1

4

High-throughput

0.553

High

545929

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.536

High

637263

PWP1
Periodic tryptophan protein 1

1

5

High-throughput

0.536

High

743416

TOR2
Serine/threonine-protein kinase TOR2

1

16

High-throughput

0.536

High

781643

DBP7
ATP-dependent RNA helicase DBP7

1

3

High-throughput

0.536

High

790369

STT4
Phosphatidylinositol 4-kinase STT4

1

3

High-throughput

0.536

High

793514

MAK5
ATP-dependent RNA helicase MAK5

1

4

High-throughput

0.536

High

806341

KOG1
Target of rapamycin complex 1 subunit KOG1

1

6

High-throughput

0.536

High

812152

LCF2
Long-chain-fatty-acid--CoA ligase 2

1

1

High-throughput

0.536

High

825326

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

1

High-throughput

0.536

High

849686

RGD2
Rho-GTPase-activating protein RGD2

1

3

High-throughput

0.536

High

919662

ASCC3
RQC trigger complex helicase SLH1

1

2

High-throughput

0.536

High

1024980

2ABA
Protein phosphatase PP2A regulatory subunit B

1

4

High-throughput

0.536

High

1030242

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.536

High

1030244

HAS1
ATP-dependent RNA helicase HAS1

1

3

High-throughput

0.536

High

893284

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

5

High-throughput

0.515

High

1030258

YSP2
Membrane-anchored lipid-binding protein YSP2

1

4

High-throughput

0.515

High

1030269

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.515

High

671026

SIS1
Protein SIS1

1

14

High-throughput

0.514

High

811372

CAJ1
Protein CAJ1

1

16

High-throughput

0.514

High

645505

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.513

High

657198

GYS1
Glycogen [starch] synthase isoform 1

1

0

High-throughput

0.513

High

763610

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.513

High

790456

PAM1
Protein PAM1

1

0

High-throughput

0.513

High

1030276

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.513

High

450742

KAD2
Adenylate kinase

1

5

High-throughput

0.501

High

460358

SYV
Valine--tRNA ligase, mitochondrial

1

5

High-throughput

0.501

High

514953

YA11A
Transposon Ty1-A Gag polyprotein

1

3

High-throughput

0.501

High

515006

YE11A
Transposon Ty1-ER1 Gag polyprotein

1

2

High-throughput

0.501

High

600706

SEC2
Rab guanine nucleotide exchange factor SEC2

1

2

High-throughput

0.501

High

794328

PBP2
PAB1-binding protein 2

1

4

High-throughput

0.501

High

795989

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

3

High-throughput

0.501

High

805426

BZZ1
Protein BZZ1

1

10

High-throughput

0.501

High

818187

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

3

High-throughput

0.501

High

825350

SHQ1
Protein SHQ1

1

1

High-throughput

0.501

High

858118

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.501

High

874301

GYP3
GTPase-activating protein GYP3

1

2

High-throughput

0.501

High

1030250

YD17A
Transposon Ty1-DR2 Gag polyprotein

1

4

High-throughput

0.501

High

1030259

BDF2
Bromodomain-containing factor 2

1

8

High-throughput

0.501

High

1030265

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.501

High

1030271

YD21A
Transposon Ty2-DR1 Gag polyprotein

1

3

High-throughput

0.501

High

1030274

YN12A
Transposon Ty1-NL2 Gag polyprotein

1

3

High-throughput

0.501

High

1030275

DFM1
DER1-like family member protein 1

1

1

High-throughput

0.501

High

711520

BEM1
Bud emergence protein 1

2

20

Small-scale

0.492

High

567701

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.489

High

803913

CIC1
Proteasome-interacting protein CIC1

1

1

High-throughput

0.489

High

816168

DPO5
rDNA transcriptional regulator POL5

1

1

High-throughput

0.489

High

830162

NOP2
25S rRNA

1

3

High-throughput

0.489

High

654741

SPA2
Protein SPA2

1

10

High-throughput

0.481

High

737021

CDC3
Cell division control protein 3

1

1

High-throughput

0.481

High

918655

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.481

High

744912

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.480

High

751236

DOM34
Protein DOM34

1

0

High-throughput

0.480

High

858285

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.480

High

924455

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

High-throughput

0.480

High

1030245

YM8V
Uncharacterized protein YMR295C

1

0

High-throughput

0.480

High

1030247

GIR2
Protein GIR2

1

0

High-throughput

0.480

High

1030253

EUC1
Transcription factor-like protein EUC1

1

0

High-throughput

0.480

High

1030260

HBT1
Protein HBT1

1

0

High-throughput

0.480

High

1030262

MPC54
Meiotic plaque component protein 54

1

0

High-throughput

0.480

High

1030264

YP191
Ubiquitin carboxyl-terminal hydrolase MIY1

1

0

High-throughput

0.480

High

674778

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

1030241

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

1030273

NOP56
Nucleolar protein 56

1

2

High-throughput

0.470

High

797774

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

734358

YMC1
Mitochondrial glycine transporter YMC1

1

10

High-throughput

0.457

High

744716

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

1

High-throughput

0.457

High

797160

AIM3
Altered inheritance of mitochondria protein 3

1

4

High-throughput

0.457

High

801702

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

13

High-throughput

0.457

High

823094

VPS27
Vacuolar protein sorting-associated protein 27

1

11

High-throughput

0.457

High

825762

MAM33
Mitochondrial acidic protein MAM33

1

3

High-throughput

0.457

High

924173

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

High-throughput

0.457

High

924686

ESBP6
Uncharacterized transporter ESBP6

1

2

High-throughput

0.457

High

925440

RCM1
25S rRNA

1

3

High-throughput

0.457

High

1030256

CORO
Coronin-like protein

1

3

High-throughput

0.457

High

524868

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

527446

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

742193

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

752619

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

810746

TCPB
T-complex protein 1 subunit beta

1

18

High-throughput

0.445

High

811138

TCPZ
T-complex protein 1 subunit zeta

1

17

High-throughput

0.445

High

824521

6P21
6-phosphofructo-2-kinase 1

1

5

High-throughput

0.445

High

844428

TCPH
T-complex protein 1 subunit eta

1

19

High-throughput

0.445

High

863695

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

512595

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

707924

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

826750

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

963653

H3
Histone H3

1

7

High-throughput

0.437

High

763105

RRP1
Ribosomal RNA-processing protein 1

2

0

High-throughput

0.322

High

1030257

URN1
Pre-mRNA-splicing factor URN1

2

0

High-throughput

0.310

High

453030

CBP8
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.279

Low

569553

CBS1
Cytochrome b translational activator protein CBS1, mitochondrial

1

0

High-throughput

0.279

Low

670198

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

678890

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.279

Low

738126

AEP1
ATPase expression protein 1, mitochondrial

1

0

High-throughput

0.279

Low

739111

PT309
Mitochondrial COX1 translation regulator PET309

1

0

High-throughput

0.279

Low

743590

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.279

Low

780305

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.279

Low

782414

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

918803

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.279

Low

918954

PESC
Pescadillo homolog

1

0

High-throughput

0.279

Low

1030263

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.279

Low

585347

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.269

Low

917235

YIP5
Protein YIP5

1

0

High-throughput

0.269

Low

518726

ADH4
Alcohol dehydrogenase 4

1

0

High-throughput

0.261

Low

645084

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.261

Low

739549

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

0

High-throughput

0.261

Low

739725

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.261

Low

745196

CDC13
Cell division control protein 13

1

0

High-throughput

0.261

Low

746545

LIPA
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.261

Low

798043

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.261

Low

812886

ELO1
Fatty acid elongase 1

1

0

High-throughput

0.261

Low

866266

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.261

Low

923306

DUS1
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]

1

0

High-throughput

0.261

Low

924586

EAF7
Chromatin modification-related protein EAF7

1

0

High-throughput

0.261

Low

924602

FYV6
Protein FYV6

1

0

High-throughput

0.261

Low

925335

YND4
Uncharacterized protein YNL034W

1

0

High-throughput

0.261

Low

1030246

YMD7
Uncharacterized protein YML037C

1

0

High-throughput

0.261

Low

1030248

YM30
Uncharacterized membrane protein YMR155W

1

0

High-throughput

0.261

Low

1030254

YMI3
Putative uncharacterized protein YML083C

1

0

High-throughput

0.261

Low

747526

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

877882

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

1030251

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025