HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SHCAF (Q9NP50)
SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein homolog)
Gene: SINHCAF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 28514442, 33961781, 22865885, 26496610, 35271311, 23752268
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0008284 - positive regulation of cell population proliferation
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 482
Hs

1 221
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024