HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FKBP4 (Q02790)
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]
Gene: FKBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 459
+	Hs
		1038702 Q9H4D1_HUMAN (1-832): 0: 708: 92.31		FKBP4_HUMAN (1-459): 1.84e-150: 437: 100.00
+	Hs
		943933 RIPK4_HUMAN (1-832): 0: 734: 100.00		FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83
+	Hs
		1106070 Q9H4D1_HUMAN (1-832): 0: 708: 92.31		FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83
+	Hs
		943941 RIPK4_HUMAN (1-832): 0: 734: 100.00		FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15
+	Hs
		1125661 Q9H4D1_HUMAN (1-832): 0: 708: 92.31		FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15
+	Hs
		731138 RIPK4_HUMAN (1-832): 0: 734: 100.00		STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42
+	Hs
		943899 RIPK4_HUMAN (1-832): 0: 734: 100.00		FKB1A_HUMAN (149-248): 1.9e-23: 96.5: 25.00
+	Hs
		731616 Q9H4D1_HUMAN (1-832): 0: 708: 92.31		STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42
+	Hs
		986866 Q9H4D1_HUMAN (1-832): 0: 708: 92.31		FKB1A_HUMAN (149-248): 1.9e-23: 96.5: 25.00
+	Hs
		1106005 ANKK1_HUMAN (321-643): 1.49e-47: 183: 18.21		FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83
+	Hs
		1038734 RIPK3_HUMAN (21-371): 4.09e-34: 139: 30.39		FKBP4_HUMAN (1-459): 1.84e-150: 437: 100.00
+	Hs
		1106149 RIPK3_HUMAN (21-371): 4.09e-34: 139: 30.39		FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83
+	Hs
		592934 ANK1_HUMAN (408-832): 4.28e-117: 393: 24.69		FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15
+	Hs
		731476 ANKK1_HUMAN (321-643): 1.49e-47: 183: 18.21		STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42
+	Hs
		731740 RIPK3_HUMAN (21-371): 4.09e-34: 139: 30.39		STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42