HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LAMC2 (Q13753)
Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma)
Gene: LAMC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation GO:0016477 - cell migration
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1193
+	Hs
		1042830 CUL3_HUMAN (1-768): 0: 951: 100.00		NOTC3_HUMAN (282-746): 4.73e-35: 148: 14.26
+	Hs
		980368 CUL3_HUMAN (1-768): 0: 951: 100.00		NOTC2_HUMAN (5-590): 8.2e-31: 134: 11.32
+	Hs
		1041528 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMB3_HUMAN (8-188): 2.19e-30: 132: 31.94
+	Hs
		804240 CUL3_HUMAN (1-768): 0: 951: 100.00		NOTC1_HUMAN (5-368): 1.5e-15: 84.6: 10.23
+	Hs
		502829 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMC1_HUMAN (248-480): 1.36e-14: 81.2: 13.75
+	Hs
		433145 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMB1_HUMAN (449-707): 5.77e-14: 79.2: 17.54
+	Hs
		1041666 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMA4_HUMAN (114-312): 4.34e-13: 76.5: 15.63
+	Hs
		172662 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMA5_HUMAN (167-420): 4.63e-12: 73.1: 11.49
+	Hs
		631064 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMA1_HUMAN (187-420): 1.72e-11: 71.2: 12.40
+	Hs
		1042862 CUL3_HUMAN (1-768): 0: 951: 100.00		JAG2_HUMAN (418-747): 2.02e-09: 64.2: 11.59
+	Hs
		877410 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMB2_HUMAN (100-284): 2.25e-09: 64.2: 14.83
+	Hs
		1041681 CUL3_HUMAN (1-768): 0: 951: 100.00		LAMA3_HUMAN (166-370): 5.92e-09: 63.1: 11.01
+	Hs
		957538 CUL3_HUMAN (1-768): 0: 951: 100.00		PGBM_HUMAN (70-183): 7.52e-09: 62.7: 17.54
+	Hs
		502830 CUL4A_HUMAN (10-768): 0: 791: 38.32		LAMC1_HUMAN (248-480): 1.36e-14: 81.2: 13.75
+	Hs
		957539 CUL4A_HUMAN (10-768): 0: 791: 38.32		PGBM_HUMAN (70-183): 7.52e-09: 62.7: 17.54