HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31911655, 25795299, 17079684
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 425
+	Hs
		1043376 CUL4B_HUMAN (10-759): 0: 927: 82.31		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1041672 CUL3_HUMAN (32-759): 0: 814: 38.23		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1043085 CUL4A_HUMAN (1-759): 0: 963: 100.00		WDR5B_HUMAN (1-254): 1.38e-58: 196: 14.83
+	Hs
		792982 CUL4A_HUMAN (1-759): 0: 963: 100.00		LIS1_HUMAN (8-257): 7.41e-58: 196: 12.77
+	Hs
		1043441 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR5B_HUMAN (1-254): 1.38e-58: 196: 14.83
+	Hs
		997714 CUL4A_HUMAN (1-759): 0: 963: 100.00		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1043114 CUL4A_HUMAN (1-759): 0: 963: 100.00		POC1B_HUMAN (2-170): 4.68e-36: 139: 9.77
+	Hs
		997715 CUL4B_HUMAN (10-759): 0: 927: 82.31		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1043469 CUL4B_HUMAN (10-759): 0: 927: 82.31		POC1B_HUMAN (2-170): 4.68e-36: 139: 9.77
+	Hs
		903208 CUL4A_HUMAN (1-759): 0: 963: 100.00		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		929446 CUL4B_HUMAN (10-759): 0: 927: 82.31		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		1043191 CUL4A_HUMAN (1-759): 0: 963: 100.00		GRWD1_HUMAN (307-404): 4.14e-14: 75.7: 23.47
+	Hs
		903209 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		1043542 CUL4B_HUMAN (10-759): 0: 927: 82.31		GRWD1_HUMAN (307-404): 4.14e-14: 75.7: 23.47
+	Hs
		997713 CUL3_HUMAN (32-759): 0: 814: 38.23		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1041647 CUL3_HUMAN (32-759): 0: 814: 38.23		TAF5_HUMAN (1-255): 1.65e-36: 143: 17.31
+	Hs
		1042101 CUL3_HUMAN (32-759): 0: 814: 38.23		POC1B_HUMAN (2-170): 4.68e-36: 139: 9.77
+	At
		186930 CUL4_ARATH (24-759): 0: 861: 57.40		MSI1_ARATH (1-167): 6.72e-18: 87.1: 7.53
+	Hs
		929445 CUL3_HUMAN (32-759): 0: 814: 38.23		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		903207 CUL3_HUMAN (32-759): 0: 814: 38.23		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61