HitPredict

Interactor 1: BACD2 (Q13829)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial)
Gene: TNFAIP1

Interactor 2: ARI1 (Q9Y4X5)
E3 ubiquitin-protein ligase ARIH1 (EC 2.3.2.31) (H7-AP2) (HHARI) (Monocyte protein 6) (MOP-6) (Protein ariadne-1 homolog) (ARI-1) (UbcH7-binding protein) (UbcM4-interacting protein) (Ubiquitin-conjugating enzyme E2-binding protein 1)
Gene: ARIH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 27565346, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 316 Hs			1 557
+	Hs
		1330042 BACD3_HUMAN (1-311): 7.45e-121: 351: 70.70		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		1264770 BACD1_HUMAN (13-316): 1.46e-119: 348: 65.13		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		1183915 KCTD9_HUMAN (3-176): 1.68e-42: 152: 24.60		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		1377912 KCTD3_HUMAN (1-130): 3.52e-26: 110: 31.34		ARI1_HUMAN (1-557): 0: 610: 100.00
+	Hs
		227868 KCTD9_HUMAN (3-176): 1.68e-42: 152: 24.60		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10
+	Hs
		228897 KCTD5_HUMAN (20-202): 8.68e-43: 149: 23.16		PRKN_HUMAN (151-388): 3.75e-55: 194: 22.10