Interactor 1: EXOS2 (Q13868)
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)
Gene: EXOSC2

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 26496610, 33961781, 24981860, 11719186
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH, ECR1_N~RNase_PH_C
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0005634 - nucleus
and 10 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 293
Hs

1 235
+ Hs
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+ At
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+ At
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+ Sp
+ Sp
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+ At
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+ Dm
+ Tb
+ Sc

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Last updated: 15 Jul 2024