HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: PCDAA (Q9Y5I2)
Protocadherin alpha-10 (PCDH-alpha-10)
Gene: PCDHA10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2221 Hs			1 948
+	Hs
		1047351 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGL_HUMAN (16-896): 0: 987: 37.24
+	Hs
		1047356 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDG6_HUMAN (2-896): 0: 936: 38.43
+	Hs
		1047353 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGI_HUMAN (26-896): 0: 905: 37.00
+	Hs
		1047352 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGJ_HUMAN (26-896): 0: 893: 38.20
+	Hs
		1047349 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDBF_HUMAN (20-775): 5.79e-179: 540: 42.22
+	Hs
		1047362 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDC2_HUMAN (1-556): 2.36e-127: 411: 23.26
+	Hs
		1047354 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGH_HUMAN (1-556): 3.16e-125: 403: 25.13
+	Hs
		1047359 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA2_HUMAN (1-595): 3.72e-124: 401: 23.45
+	Hs
		1047323 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA6_HUMAN (1-595): 8.25e-124: 400: 24.06
+	Hs
		1047361 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA1_HUMAN (1-595): 1.71e-123: 400: 23.13
+	Hs
		1047324 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDA4_HUMAN (1-595): 2.83e-123: 399: 23.45
+	Hs
		1047358 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGA_HUMAN (1-579): 7.52e-122: 395: 24.04
+	Hs
		1047322 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGG_HUMAN (1-556): 1.05e-120: 392: 24.26
+	Hs
		1047325 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDAC_HUMAN (1-595): 1.15e-118: 386: 23.66
+	Hs
		1047355 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDGF_HUMAN (1-556): 1.87e-116: 380: 26.64
+	Hs
		1047347 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDB5_HUMAN (357-922): 1.25e-59: 220: 17.05
+	Hs
		1047357 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDG3_HUMAN (4-233): 9.42e-33: 138: 15.64
+	Hs
		1047348 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDB2_HUMAN (4-233): 1.85e-30: 131: 19.84
+	Hs
		1047258 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCDC1_HUMAN (4-232): 2.36e-25: 115: 19.34
+	Hs
		1303362 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PCDGG_HUMAN (1-556): 1.05e-120: 392: 24.26