HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: MAP7 (Q14244)
Ensconsin (Epithelial microtubule-associated protein of 115 kDa) (E-MAP-115) (Microtubule-associated protein 7) (MAP-7)
Gene: MAP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0005875 - microtubule associated complex GO:0015630 - microtubule cytoskeleton GO:0030424 - axon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1278 Hs			1 749
+	Hs
		997150 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		CAMP2_HUMAN (97-683): 5.02e-51: 195: 16.39
+	Hs
		1051300 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		MA7D1_HUMAN (20-682): 5.64e-49: 187: 30.17
+	Hs
		1051425 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		MA7D2_HUMAN (26-681): 1.97e-39: 157: 24.54
+	Hs
		1051316 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		CAMP1_HUMAN (71-560): 9.72e-29: 125: 15.53
+	Hs
		1051352 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		MA7D3_HUMAN (23-638): 5.84e-26: 116: 19.23
+	Hs
		1051507 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		TNIK_HUMAN (31-501): 3.32e-24: 111: 14.14
+	Hs
		1052102 CLIP4_HUMAN (6-95): 3.79e-26: 118: 42.22		MAP7_HUMAN (1-749): 4.28e-87: 292: 100.00
+	Hs
		675169 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		MAP7_HUMAN (1-749): 4.28e-87: 292: 100.00
+	Hs
		1051385 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		TITIN_HUMAN (68-741): 1.24e-11: 70.9: 8.66
+	Hs
		997223 KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85		CAMP2_HUMAN (97-683): 5.02e-51: 195: 16.39
+	Hs
		1108854 CLIP4_HUMAN (6-95): 3.79e-26: 118: 42.22		MA7D1_HUMAN (20-682): 5.64e-49: 187: 30.17
+	Hs
		675176 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		MA7D1_HUMAN (20-682): 5.64e-49: 187: 30.17
+	Hs
		675218 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		MA7D2_HUMAN (26-681): 1.97e-39: 157: 24.54
+	Hs
		876511 KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85		AFAD_HUMAN (112-729): 1.82e-27: 121: 12.28
+	Hs
		1078925 CLIP2_HUMAN (26-552): 7.47e-22: 104: 17.63		ITSN1_HUMAN (212-627): 5.03e-37: 152: 14.29
+	Hs
		675181 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		CAMP1_HUMAN (71-560): 9.72e-29: 125: 15.53
+	Hs
		725139 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		ANK2_HUMAN (65-618): 3.44e-25: 114: 12.28
+	Hs
		725147 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Hs
		675196 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		MA7D3_HUMAN (23-638): 5.84e-26: 116: 19.23
+	Hs
		1232232 CLIP4_HUMAN (6-95): 3.79e-26: 118: 42.22		TITIN_HUMAN (68-741): 1.24e-11: 70.9: 8.66