HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 1374
+	Mm
		222845 MYH10_MOUSE (664-1275): 2.98e-22: 106: 10.29		ACK1_MOUSE (55-976): 4.88e-124: 413: 20.25
+	Mm
		222875 MYH9_MOUSE (826-1275): 8.37e-15: 82.2: 10.13		ACK1_MOUSE (55-976): 4.88e-124: 413: 20.25
+	Hs
		384829 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		411758 MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		433818 MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64		LYN_HUMAN (109-410): 9.62e-106: 347: 24.75
+	Hs
		665375 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		EPHA3_HUMAN (12-404): 1.11e-104: 358: 23.74
+	Hs
		411581 DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		433620 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		LYN_HUMAN (109-410): 9.62e-106: 347: 24.75
+	Hs
		433558 DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64		LYN_HUMAN (109-410): 9.62e-106: 347: 24.75
+	Hs
		412058 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		411983 DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		385569 KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		385396 TBCB_HUMAN (19-96): 2.34e-32: 128: 46.91		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384385 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		725268 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		ALK_HUMAN (109-386): 2.69e-32: 139: 32.99
+	Hs
		384981 MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384384 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384210 DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		725069 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ALK_HUMAN (109-386): 2.69e-32: 139: 32.99