HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 703
+	Hs
		1051492 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		DAPLE_HUMAN (37-586): 4.1e-41: 164: 17.08
+	Hs
		1051301 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		148801 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		725033 KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		725097 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH11_HUMAN (1-585): 5.28e-26: 116: 10.94
+	Hs
		528432 MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87		MYH8_HUMAN (2-701): 1.11e-26: 119: 11.69
+	Hs
		725095 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		528435 MYH4_HUMAN (726-1276): 1.05e-18: 94.9: 10.20		MYH8_HUMAN (2-701): 1.11e-26: 119: 11.69
+	Hs
		522657 MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80		MYH4_HUMAN (2-477): 5.27e-17: 87.9: 10.65
+	Hs
		724687 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148461 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		502901 MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Hs
		502921 CLIP4_HUMAN (6-95): 3.79e-26: 118: 42.22		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Hs
		528356 MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71		MYH6_HUMAN (300-700): 3.66e-13: 75.5: 11.47
+	Hs
		675177 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		522585 MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80		MYH7_HUMAN (367-695): 1.25e-09: 64: 10.00
+	Hs
		502933 MYH4_HUMAN (726-1276): 1.05e-18: 94.9: 10.20		MYH3_HUMAN (1-450): 1.24e-13: 76.9: 12.17
+	Hs
		675226 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Rn
		222472 MRCKA_RAT (154-593): 3.97e-21: 102: 15.78		MRCKA_RAT (80-483): 2.52e-09: 62.9: 16.67