HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: JIP3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)
Gene: MAPK8IP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 19211056
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030424 - axon
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 1336
+	Hs
		724971 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ARHGH_HUMAN (375-1331): 4.89e-152: 508: 20.28
+	Hs
		148801 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		725033 KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		725095 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH10_HUMAN (243-769): 2.9e-24: 113: 8.89
+	Hs
		724687 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Rn
		222472 MRCKA_RAT (154-593): 3.97e-21: 102: 15.78		MRCKA_RAT (277-691): 9.07e-23: 108: 10.43
+	Hs
		148461 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		724943 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		MY18A_HUMAN (189-793): 1.74e-25: 117: 9.00
+	Hs
		1137871 MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64		MRCKA_HUMAN (2-407): 2.77e-19: 96.9: 12.93
+	Mm
		93570 MYH9_MOUSE (826-1275): 8.37e-15: 82.2: 10.13		DESP_MOUSE (31-675): 1.34e-21: 104: 11.78
+	Hs
		724810 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ROCK1_HUMAN (2-581): 2.57e-21: 103: 9.37
+	Hs
		724686 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		725189 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH14_HUMAN (80-569): 1.98e-11: 71.2: 13.69
+	Hs
		675221 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		AKAP9_HUMAN (45-563): 1.97e-11: 71.2: 13.56
+	Hs
		148460 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		148359 DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		725097 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH11_HUMAN (381-691): 8.22e-09: 62.6: 11.75
+	Hs
		551596 DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64		DESP_HUMAN (27-706): 3.94e-16: 86.8: 11.43
+	Hs
		724895 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		MYH14_HUMAN (80-569): 1.98e-11: 71.2: 13.69