Protein: SRS11
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)

Gene: SRS11, SRSF11
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q05519

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1051530

PUF60
Poly(U)-binding-splicing factor PUF60

6

9

High-throughput

0.954

High

1006352

SRPK2
SRSF protein kinase 2

6

16

High-throughput

0.948

High

1051502

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

4

5

High-throughput

0.904

High

1051468

RBM39
RNA-binding protein 39

4

8

High-throughput

0.903

High

1051470

RNPS1
RNA-binding protein with serine-rich domain 1

4

8

Small-scale

0.897

High

1051514

SRPK1
SRSF protein kinase 1

2

15

High-throughput

0.811

High

329736

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

2

1

High-throughput

0.789

High

1051453

SRS11
Serine/arginine-rich splicing factor 11

2

9

High-throughput

0.783

High

1051501

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

2

5

High-throughput

0.754

High

1051527

PAK5
Serine/threonine-protein kinase PAK 5

1

1

Small-scale

0.724

High

997664

CSK21
Casein kinase II subunit alpha

1

5

High-throughput

0.710

High

1025328

CDK6
Cyclin-dependent kinase 6

1

3

Small-scale

0.710

High

134692

SAP18
Histone deacetylase complex subunit SAP18

1

2

High-throughput

0.691

High

284126

SRS10
Serine/arginine-rich splicing factor 10

1

8

High-throughput

0.691

High

889085

RBM25
RNA-binding protein 25

1

10

High-throughput

0.691

High

889403

CLK1
Dual specificity protein kinase CLK1

1

9

High-throughput

0.691

High

889556

CLK2
Dual specificity protein kinase CLK2

1

9

High-throughput

0.691

High

889715

CLK3
Dual specificity protein kinase CLK3

1

9

High-throughput

0.691

High

988091

TRA2B
Transformer-2 protein homolog beta

1

11

High-throughput

0.691

High

1051455

SRSF4
Serine/arginine-rich splicing factor 4

1

11

High-throughput

0.691

High

1051459

SRSF9
Serine/arginine-rich splicing factor 9

1

11

High-throughput

0.691

High

1051460

SRSF6
Serine/arginine-rich splicing factor 6

1

12

High-throughput

0.691

High

1051461

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

5

High-throughput

0.691

High

1051462

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

7

High-throughput

0.691

High

1051465

TRA2A
Transformer-2 protein homolog alpha

1

7

High-throughput

0.691

High

1051503

SRS12
Serine/arginine-rich splicing factor 12

1

10

High-throughput

0.691

High

1051508

RMXL1
RNA binding motif protein, X-linked-like-1

1

7

High-throughput

0.691

High

1051524

RBM22
Pre-mRNA-splicing factor RBM22

1

5

High-throughput

0.691

High

1051533

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

7

High-throughput

0.691

High

1051535

SRPK3
SRSF protein kinase 3

1

15

High-throughput

0.691

High

685518

U2AF2
Splicing factor U2AF 65 kDa subunit

1

10

Small-scale

0.680

High

140236

SDCB1
Syntenin-1

3

2

High-throughput

0.675

High

1051486

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

1

Small-scale

0.667

High

1051481

Z385C
Zinc finger protein 385C

1

2

High-throughput

0.665

High

67824

SRRM4
Serine/arginine repetitive matrix protein 4

3

0

High-throughput

0.626

High

1029455

SRSF2
Serine/arginine-rich splicing factor 2

1

5

Small-scale

0.621

High

1051454

SRSF1
Serine/arginine-rich splicing factor 1

1

12

Small-scale

0.621

High

400694

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.618

High

472669

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

8

High-throughput

0.618

High

1032913

EWS
RNA-binding protein EWS

1

6

High-throughput

0.618

High

1051505

CELF1
CUGBP Elav-like family member 1

1

3

High-throughput

0.618

High

1051521

RC3H2
Roquin-2

1

6

High-throughput

0.618

High

1051529

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

1051534

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

6

High-throughput

0.618

High

1051536

TRI33
E3 ubiquitin-protein ligase TRIM33

1

2

High-throughput

0.618

High

577428

ETS1
Protein C-ets-1

2

2

High-throughput

0.614

High

966225

1433G
14-3-3 protein gamma

2

10

High-throughput

0.611

High

1051490

ZCH18
Zinc finger CCCH domain-containing protein 18

2

7

High-throughput

0.611

High

685167

PAX6
Paired box protein Pax-6

2

4

High-throughput

0.606

High

1051484

DUS29
Dual specificity phosphatase 29

2

1

High-throughput

0.606

High

1051496

LNX2
Ligand of Numb protein X 2

3

4

High-throughput

0.596

High

241469

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

371834

MYC
Myc proto-oncogene protein

2

9

High-throughput

0.584

High

1051531

DACH1
Dachshund homolog 1

2

0

High-throughput

0.580

High

1051479

HYI
Putative hydroxypyruvate isomerase

2

1

High-throughput

0.578

High

1051478

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.575

High

1051497

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.575

High

109170

G4XUV3
Putative hydroxypyruvate isomerase

2

1

High-throughput

0.558

High

716672

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

2

1

High-throughput

0.553

High

1051483

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

0

High-throughput

0.549

High

280590

PR40A
Pre-mRNA-processing factor 40 homolog A

1

12

High-throughput

0.536

High

1051464

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.536

High

1051466

CUL3
Cullin-3

1

8

High-throughput

0.536

High

1051472

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.536

High

1051477

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.536

High

1051480

PR38B
Pre-mRNA-splicing factor 38B

1

3

High-throughput

0.536

High

1051487

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

3

High-throughput

0.536

High

1051491

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

1051493

SRRM1
Serine/arginine repetitive matrix protein 1

1

8

High-throughput

0.536

High

1051512

YTDC1
YTH domain-containing protein 1

1

3

High-throughput

0.536

High

1051513

UIF
UAP56-interacting factor

1

1

High-throughput

0.536

High

1051519

PININ
Pinin

1

1

High-throughput

0.536

High

1051526

BCLF1
Bcl-2-associated transcription factor 1

1

8

High-throughput

0.536

High

1051532

GPTC8
G patch domain-containing protein 8

1

7

High-throughput

0.536

High

1051537

SRRM2
Serine/arginine repetitive matrix protein 2

1

8

High-throughput

0.536

High

1051509

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.518

High

1051482

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.517

High

1051506

H2B1H
Histone H2B type 1-H

1

12

High-throughput

0.515

High

1051485

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.515

High

470288

NEP
Neprilysin

1

0

Small-scale

0.513

High

185627

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

1028162

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.500

High

1051498

ZCH10
Zinc finger CCHC domain-containing protein 10

1

2

High-throughput

0.489

High

893834

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.481

High

1051489

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

8

High-throughput

0.481

High

1051463

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.480

High

223524

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

7

High-throughput

0.479

High

247845

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

259839

BRD4
Bromodomain-containing protein 4

1

12

High-throughput

0.479

High

319696

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

335821

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.479

High

342841

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.479

High

363167

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

406091

MYCN
N-myc proto-oncogene protein

1

9

High-throughput

0.479

High

446936

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

541965

TOP1
DNA topoisomerase 1

1

3

Small-scale

0.479

High

588522

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

606673

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

695271

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

766475

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

768014

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

830606

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

878999

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

8

High-throughput

0.479

High

904631

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

934508

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

970378

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

979542

H4
Histone H4

1

6

High-throughput

0.479

High

1008693

RED1
Double-stranded RNA-specific editase 1

1

10

High-throughput

0.479

High

1024518

VIGLN
Vigilin

1

7

High-throughput

0.479

High

1045202

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

1051456

EP300
Histone acetyltransferase p300

1

13

High-throughput

0.479

High

1051457

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.479

High

1051458

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

1

High-throughput

0.479

High

1051467

CUL4B
Cullin-4B

1

8

High-throughput

0.479

High

1051469

DHX8
ATP-dependent RNA helicase DHX8

1

6

High-throughput

0.479

High

1051471

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

1051475

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1051476

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1051492

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1051499

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1051516

DDX23
Probable ATP-dependent RNA helicase DDX23

1

5

High-throughput

0.479

High

1051525

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

583294

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

1048302

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

1051474

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.458

High

1051515

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

1051517

IN80B
INO80 complex subunit B

1

0

High-throughput

0.458

High

1051522

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.458

High

429764

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

1051500

RAB2B
Ras-related protein Rab-2B

1

2

High-throughput

0.439

High

272099

OBSL1
Obscurin-like protein 1

1

12

High-throughput

0.437

High

411784

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

995551

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.437

High

1051488

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1051495

RHG24
Rho GTPase-activating protein 24

1

1

High-throughput

0.437

High

1051507

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

1051511

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

1051520

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.437

High

1051523

LUC7L
Putative RNA-binding protein Luc7-like 1

1

2

High-throughput

0.437

High

1051528

VPS29
Vacuolar protein sorting-associated protein 29

1

1

High-throughput

0.437

High

230176

S28A2
Sodium/nucleoside cotransporter 2

1

1

High-throughput

0.407

High

952121

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

12

High-throughput

0.407

High

225193

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

3

0

High-throughput

0.352

High

1051504

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.299

High

813069

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.282

High

1051538

GUAD
Guanine deaminase

1

0

High-throughput

0.279

Low

1051494

RBFA
Putative ribosome-binding factor A, mitochondrial

1

0

High-throughput

0.249

Low

1051518

TOLIP
Toll-interacting protein

1

0

High-throughput

0.249

Low

1051473

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.232

Low

1051510

S41A3
Solute carrier family 41 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025