HitPredict

Interactor 1: NMDZ1 (Q05586)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) (hNR1)
Gene: GRIN1

Interactor 2: NETO1 (Q8TDF5)
Neuropilin and tolloid-like protein 1 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1)
Gene: NETO1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23621516
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANF_receptor~CUB, CUB~Lig_chan, Ldl_recept_a~Lig_chan, CUB~Lig_chan-Glu_bd
Common GO terms	GO:0008542 - visual learning GO:0014069 - postsynaptic density GO:0060076 - excitatory synapse GO:0098839 - postsynaptic density membrane GO:2000463 - positive regulation of excitatory postsynaptic potential
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 938 Hs			1 533
+	Mm
		771498 NMDZ1_MOUSE (1-938): 0: 930: 99.04		NETO1_MOUSE (1-533): 0: 637: 95.69
+	Hs
		1092404 GRIK2_HUMAN (3-900): 0: 742: 22.57		NETO1_HUMAN (1-533): 0: 642: 100.00
+	Hs
		1098526 NMDE2_HUMAN (4-938): 0: 650: 23.83		NETO1_HUMAN (1-533): 0: 642: 100.00
+	Mm
		1029236 NMDE2_MOUSE (4-938): 0: 644: 23.63		NETO1_MOUSE (1-533): 0: 637: 95.69
+	Hs
		1088779 NMDE1_HUMAN (2-923): 0: 604: 24.11		NETO1_HUMAN (1-533): 0: 642: 100.00
+	Rn
		93301 NMDE1_RAT (1-923): 0: 601: 24.13		D4AAD6_RAT (1-533): 0: 638: 95.50
+	Mm
		771430 NMDE1_MOUSE (1-923): 0: 600: 24.24		NETO1_MOUSE (1-533): 0: 637: 95.69