HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: AIF1L (Q9BQI0)
Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2)
Gene: AIF1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0051017 - actin filament bundle assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 150
+	Hs
		1052096 CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00		EFHD1_HUMAN (1-109): 2.99e-35: 124: 31.19
+	Hs
		1365566 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		EFHD2_HUMAN (1-109): 3.04e-29: 108: 29.36
+	Hs
		516563 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		CALM3_HUMAN (41-149): 9.61e-30: 107: 23.21
+	Dm
		1202456 Q59E59_DROME (2-660): 1.2e-24: 112: 11.67		EFHD2_DROME (24-120): 1.4e-30: 111: 29.90
+	Dm
		1404025 MYSN_DROME (2-638): 2.86e-24: 111: 10.72		EFHD2_DROME (24-120): 1.4e-30: 111: 29.90
+	Hs
		773244 MYH10_HUMAN (1-631): 5.25e-22: 104: 9.40		EFHD2_HUMAN (1-109): 3.04e-29: 108: 29.36
+	Hs
		772947 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		EFHD2_HUMAN (1-109): 3.04e-29: 108: 29.36
+	Hs
		692660 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		CALL3_HUMAN (41-149): 1.05e-27: 101: 22.32
+	Hs
		516591 MYO5C_HUMAN (13-485): 5.43e-09: 62.2: 14.38		CALM3_HUMAN (41-149): 9.61e-30: 107: 23.21
+	Dm
		56404 A1ZA72_DROME (138-632): 5.08e-09: 62.2: 17.72		CALM_DROME (41-149): 1.74e-29: 106: 23.21
+	Hs
		587830 DESP_HUMAN (13-640): 3.04e-22: 105: 14.35		CALL5_HUMAN (49-112): 2.96e-09: 53.9: 28.13