HitPredict

Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 530
+	Hs
		369598 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369479 PPID_HUMAN (5-369): 4.48e-66: 216: 18.06		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370658 FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377276 PPID_HUMAN (5-369): 4.48e-66: 216: 18.06		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		369442 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369072 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369544 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1025273 FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		377261 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		415156 FKBP4_MOUSE (72-404): 2.2e-24: 106: 18.86		GCR_MOUSE (3-495): 7.76e-103: 328: 23.23
+	Hs
		377132 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		415159 FKBP5_MOUSE (81-405): 2.57e-19: 91.5: 16.89		GCR_MOUSE (3-495): 7.76e-103: 328: 23.23
+	Hs
		437638 PPID_HUMAN (5-369): 4.48e-66: 216: 18.06		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		487372 PPID_HUMAN (5-369): 4.48e-66: 216: 18.06		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		118677 AIP_HUMAN (97-369): 4.45e-54: 184: 18.94		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		414489 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		414449 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		437634 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		MCR_HUMAN (141-408): 5.92e-38: 150: 34.03
+	Hs
		487347 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487173 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59