HitPredict

Interactor 1: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK

Interactor 2: AP3S1 (Q92572)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 659 Hs			1 193
+	Hs
		908219 BMX_HUMAN (5-658): 0: 650: 47.62		AP3S1_HUMAN (1-193): 5.68e-74: 223: 100.00
+	Hs
		908231 BMX_HUMAN (5-658): 0: 650: 47.62		AP3M1_HUMAN (1-188): 7.1e-46: 157: 18.62
+	Hs
		440162 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		AP3S1_HUMAN (1-193): 5.68e-74: 223: 100.00
+	Hs
		902871 BLK_HUMAN (156-653): 3.08e-164: 482: 35.98		AP3S1_HUMAN (1-193): 5.68e-74: 223: 100.00
+	Hs
		72388 A9UF07_HUMAN (34-659): 1.97e-162: 511: 32.41		AP2M1_HUMAN (1-186): 2.6e-49: 167: 11.83
+	Hs
		362343 ABL1_HUMAN (181-659): 3.42e-164: 502: 38.76		AP2M1_HUMAN (1-186): 2.6e-49: 167: 11.83
+	Hs
		440255 LCK_HUMAN (205-653): 3.74e-171: 499: 38.19		AP3M1_HUMAN (1-188): 7.1e-46: 157: 18.62