HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35016035
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 377
+	Hs
		932185 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		932318 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		891660 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		903110 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		792947 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		792968 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		ACTG_HUMAN (4-377): 0: 599: 94.39