HitPredict

Interactor 1: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Interactor 2: FBRS (Q9HAH7)
Probable fibrosin-1
Gene: FBRS

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	27705803, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 460
+	Hs
		1404772 RING2_HUMAN (8-406): 4.92e-100: 302: 54.25		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		116963 RING2_HUMAN (8-406): 4.92e-100: 302: 54.25		J3KNZ9_HUMAN (1-460): 2.79e-175: 518: 100.00
+	Hs
		765900 BMI1_HUMAN (31-378): 4.08e-63: 207: 14.16		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		766122 PCGF2_HUMAN (31-377): 1.45e-41: 151: 14.37		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1418398 PCGF6_HUMAN (31-157): 1.03e-40: 149: 23.08		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1055861 RING1_HUMAN (1-406): 2.02e-114: 342: 100.00		FBSL_HUMAN (2-327): 3.73e-103: 332: 35.31
+	Hs
		1412820 PCGF1_HUMAN (25-133): 3.55e-40: 145: 25.00		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1185949 PCGF3_HUMAN (34-224): 6.22e-39: 141: 17.53		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1055833 RING1_HUMAN (1-406): 2.02e-114: 342: 100.00		AUTS2_HUMAN (1-283): 2.4e-90: 300: 43.62
+	Hs
		1404775 RING2_HUMAN (8-406): 4.92e-100: 302: 54.25		FBSL_HUMAN (2-327): 3.73e-103: 332: 35.31
+	Hs
		1361276 RING2_HUMAN (8-406): 4.92e-100: 302: 54.25		AUTS2_HUMAN (1-283): 2.4e-90: 300: 43.62
+	Mm
		398 RING2_MOUSE (8-406): 2.96e-100: 303: 54.25		AUTS2_MOUSE (1-270): 6.07e-90: 299: 44.91
+	Mm
		205493 RING1_MOUSE (1-406): 2.18e-118: 352: 96.55		Q6PED7_MOUSE (74-270): 7.82e-62: 213: 43.13
+	Mm
		1243995 RING2_MOUSE (8-406): 2.96e-100: 303: 54.25		Q6PED7_MOUSE (74-270): 7.82e-62: 213: 43.13
+	Hs
		1418400 PCGF6_HUMAN (31-157): 1.03e-40: 149: 23.08		FBSL_HUMAN (2-327): 3.73e-103: 332: 35.31
+	Hs
		1185951 PCGF3_HUMAN (34-224): 6.22e-39: 141: 17.53		FBSL_HUMAN (2-327): 3.73e-103: 332: 35.31
+	Hs
		1361277 PCGF6_HUMAN (31-157): 1.03e-40: 149: 23.08		AUTS2_HUMAN (1-283): 2.4e-90: 300: 43.62
+	Mm
		394 PCGF3_MOUSE (34-224): 1.29e-40: 146: 18.09		AUTS2_MOUSE (1-270): 6.07e-90: 299: 44.91
+	Hs
		1185929 PCGF3_HUMAN (34-224): 6.22e-39: 141: 17.53		AUTS2_HUMAN (1-283): 2.4e-90: 300: 43.62
+	Mm
		1243993 PCGF3_MOUSE (34-224): 1.29e-40: 146: 18.09		Q6PED7_MOUSE (74-270): 7.82e-62: 213: 43.13