HitPredict

Interactor 1: DSC3 (Q14574)
Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP)
Gene: DSC3

Interactor 2: CLC4A (Q9UMR7)
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)
Gene: CLEC4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Lectin_C
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 237
+	Hs
		1055867 DSC3_HUMAN (1-896): 0: 847: 100.00		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		1055845 DSC3_HUMAN (1-896): 0: 847: 100.00		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1357316 PCDGA_HUMAN (1-818): 0: 705: 18.46		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		606307 CADH3_HUMAN (10-891): 0: 577: 27.49		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1357314 PCDBD_HUMAN (2-485): 8.17e-83: 285: 16.47		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1263941 PCDGH_HUMAN (2-464): 7.18e-93: 315: 15.98		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		580249 CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		522269 CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		580243 CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55		CLC4G_HUMAN (70-232): 1.34e-39: 139: 27.22