Interactor 1: CASP8 (Q14790)
Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8
Interactor 2: MALT1 (Q9UDY8)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)
Gene: MALT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 0.90 | 0.613 |
The method score is based on:
Property | Details |
---|---|
Experiments | 22267217 |
Identification Methods | anti bait coimmunoprecipitation |
Interaction Type | association, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | MALT1_Ig~Peptidase_C14, Peptidase_C14~Peptidase_C14 |
Common GO terms | GO:0004197 - cysteine-type endopeptidase activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006508 - proteolysis GO:0008233 - peptidase activity and 5 others more... |
Homologous interactions | 0 |
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Last updated: 15 Jul 2024