Protein: PEP3
Vacuolar membrane protein PEP3 (Carboxypeptidase Y-deficient protein 3) (Vacuolar morphogenesis protein 8) (Vacuolar protein sorting-associated protein 18) (Vacuolar protein-targeting protein 18)

Gene: PEP3
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: P27801

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006895 - Golgi to endosome transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

698091

PEP3
Vacuolar membrane protein PEP3

2

19

Small-scale

0.767

High

698107

VPS41
Vacuolar protein sorting-associated protein 41

13

18

Small-scale

0.761

High

635023

VPS33
Vacuolar protein sorting-associated protein 33

11

19

Small-scale

0.761

High

556592

PEP5
E3 ubiquitin-protein ligase PEP5

9

10

Small-scale

0.760

High

698124

VAM6
Vacuolar morphogenesis protein 6

10

19

Small-scale

0.756

High

698109

VPS8
Vacuolar protein sorting-associated protein 8

7

8

Small-scale

0.750

High

698120

VPS16
Vacuolar protein sorting-associated protein 16

6

14

Small-scale

0.739

High

661741

VPS3
Vacuolar protein sorting-associated protein 3

7

4

Small-scale

0.737

High

698130

VAM3
Syntaxin VAM3

5

20

Small-scale

0.721

High

698096

VAM7
Vacuolar morphogenesis protein 7

5

7

Small-scale

0.718

High

698098

YPT7
Ypt/Rab-type GTPase YPT7

3

14

Small-scale

0.660

High

698094

PEP7
Vacuolar segregation protein PEP7

2

3

Small-scale

0.600

High

698102

AAP1
Alanine/arginine aminopeptidase

2

0

High-throughput

0.595

High

392343

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.584

High

698122

VTI1
t-SNARE VTI1

2

6

Small-scale

0.584

High

535985

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

2

High-throughput

0.536

High

698093

PP12
Serine/threonine-protein phosphatase PP1-2

2

5

High-throughput

0.521

High

698117

PROA
Gamma-glutamyl phosphate reductase

1

1

High-throughput

0.515

High

698115

MON1
Vacuolar fusion protein MON1

1

8

Small-scale

0.508

High

698103

CCZ1
Vacuolar fusion protein CCZ1

1

3

Small-scale

0.501

High

698110

KC13
Casein kinase I homolog 3

1

4

Small-scale

0.501

High

698127

AP3D
AP-3 complex subunit delta

1

9

Small-scale

0.501

High

368611

PMG1
Phosphoglycerate mutase 1

1

2

High-throughput

0.500

High

452840

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.500

High

453455

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.500

High

698101

YPT52
GTP-binding protein YPT52

1

19

Small-scale

0.481

High

698118

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

High-throughput

0.481

High

578964

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

649798

VPS34
Phosphatidylinositol 3-kinase VPS34

1

3

High-throughput

0.479

High

672627

BPH1
Beige protein homolog 1

1

2

High-throughput

0.479

High

698092

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

698095

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

698119

BECN1
Vacuolar protein sorting-associated protein 30

1

1

High-throughput

0.479

High

698121

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.479

High

698128

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

698129

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

438635

SC160
Protein SCP160

1

0

High-throughput

0.458

High

386599

TBB
Tubulin beta chain

1

2

High-throughput

0.457

High

486063

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.457

High

590558

HSP26
Heat shock protein 26

1

3

High-throughput

0.457

High

481515

HSP73
Heat shock protein SSA3

1

7

High-throughput

0.445

High

523241

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

526080

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

544034

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

675766

MAS5
Mitochondrial protein import protein MAS5

1

8

High-throughput

0.445

High

698105

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

698108

XDJ1
DnaJ protein homolog XDJ1

1

8

High-throughput

0.445

High

698112

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

698116

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.445

High

698126

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

16

Small-scale

0.445

High

506434

U5072
UPF0507 protein YML002W

1

2

Small-scale

0.439

High

698097

SC61A
Protein transport protein SEC61

1

4

High-throughput

0.437

High

698104

KPR3
Ribose-phosphate pyrophosphokinase 3

1

2

High-throughput

0.407

High

698099

PP2C1
Protein phosphatase 2C homolog 1

1

0

High-throughput

0.279

Low

698123

SML1
Ribonucleotide reductase inhibitor protein SML1

1

0

High-throughput

0.269

Low

698111

IMB4
Importin subunit beta-4

1

0

High-throughput

0.261

Low

624720

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

698100

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

698106

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

698113

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

698125

HBT1
Protein HBT1

1

0

High-throughput

0.249

Low

698114

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025